x
uploads/virulence.jpg

virulence n.1.有毒,毒力,毒性。2.刻毒,惡毒,惡意。3.【醫...

virulent

A few years latter the research showed , vp2 hydrophilic region and antigen variant and virulence of ibdv had very affinity . in order to lucubrate difference of virulence and antigen , and validate correntness of sequencing result , the test adopted sandwich enzyme - liked immunosorbent assay ( elisa ) and antigen caprure - elisa to determine virulence and antigen . and validate correntness of above - mentioned result 而近幾年的研究表明, vp2高變區與ibdv的抗原變異和毒力強弱有密切的關系,為進一步了解強弱毒株毒力和抗原的差別,并進一步證實測序結果的正確性,本試驗采用雙抗夾心elisa和ac - elisa的方法分別對其毒力和抗原進行了測定,并通過動物試驗證實了,其結果與序列分析結果基本一致。

The result shows that a vvibdv strain was obtained , the above work lay a important role for further studying on the molecular biological mechanism of antigenic drift and virulence variation of ibdv , molecular epedimiology , it also provided the basis for recombinant and gene deleted vaccine of ibdv 本實驗可以幫助我們進一步探討ibdv抗原性漂移和毒力變化的分子生物學機制,追溯ibdv的起源,理解病毒的傳播方式。同時也為研制開發基因重組疫苗和缺失疫苗打下一定的基礎。

Using conjunction mobilization , we screened the mutant of eaggec 17 - 2 with the mutant phenotype by one step . compared mutant and eaggec 17 - 2 , the experiments such as growth under iron - deficient conditions , virulence testing to the mouse , and ybt biosynthesis and regulation showed that ybtp , ybtq and ybtx genes have no significant effects on iron uptake , mouse virulen Eaggec17毛攜帶的hpi毒力島的功能研究eaggec172的ybtp 、 ybtqyybtx突變株沒有表現出鐵缺陷培養條件下的生長抑制表型,對ybt的合成無明顯影響;對野生株與ybtp突變株的鼠毒力對比實驗表明, lds 。

By morphologic examination , structure characteristics ^ biological property n serological tests and pathology characteristic study , this virus was identified as the medium virulence chicken . new castle disease virus ( ndv ) , whose pathology characteristics were appeared different from those of the standard virulence ndv . la sola vaccine could not give good protection against the infection of this virus isolate 用spf雞胚在吉林省患病雞群中分離到一株病毒,經病毒形態學、結構特征、生物學、血清學及致病性等試驗研究,確定該病毒為雞新城疫強毒,對lasota免疫雞的致病性及其致死率與雞新城疫標準強毒e _ 9f _ ( 48 )對比差異顯著, lasota疫苗對該株病毒免疫保護效果不理想。

The results also indicated that the virulence of the most ibdv field collected in recent years was between the typical very virulent and standard virulent strains . a very virulent strain gx8 / 99 of ibdv was studied for its mortality in spf chickens and commercial egg - type chickens at different age inoculated with bursal suspension of 20 - 2000 eld50 in repeated experiments 選擇致病性最強的來自廣西的gx8 99株,在對法氏囊懸液中病毒用雞胚半數致死量( eld _ ( 50 ) )定量測定后,在不同年齡的spf雞和商品代蛋用型塢多次重復地比較研究了該毒株的致病性。

Two amino acid substitutions near the vp2 - vp4 cleavage site were identified in the virulent strain jz2000 and might be involved in increased virulence of the virus . phylogenetic analyses indicated that these two strains were most closely related to some european strains but distinct from wibdv and variant strains 分子系統進化樹分析表明, zj2000株和jd1株與cu - 1 、 p2 、 cef94 、 harbin等毒株的關系最近,而與歐洲、香港、日本的超強毒株和美國的變異株相對較遠。

Newcastle disease virus ( ndv ) is grouped under the family of paramyxoviridae , it causes serious infectious disease and incurred great losses to poultry industry . f and hn protein were main glycoproteins , which affect the virulence of the virus 新城疫病毒( newcastlediseasevirus , ndv )屬于副粘病毒科( paramyxoviridae )副粘病毒亞科( paramyxovirinae )腮腺炎病毒屬( rubulavirus )的成員,其主要結構蛋白融合蛋白( f )和血凝素-神經氨酸酶( hn )與其致病性密切相關。

The results determined by the criteria of virulence and pathogenicity with traditional ndv standard is not identical all the time with facts in the field for all the isolates . the isolation and identification of apmv - 1 were performed on the field cases of suspected apmv - 1 infection in guangxi poultry 本研究對來自廣西的可疑apmv - 1感染的各種禽類進行了病毒分離和鑒定,并選取代表性分離株按雞ndv的經典方法進行了毒力的測定和致病性試驗。

All these results suggested that the cause of 4d1 culture inhibiting the pathogenicity of scg1 is the decreased concentration of ahl molecule in scg1 cells , when presenting aii protein in 4d1 cells , and then not inducing the expression of virulence genes of scg 1 at low concentration of ahl molecules 由此推測,蘇云金芽胞桿菌影響病原菌致病性的原因在于降低了病原菌細胞內ahl類信號分子的濃度,使其達不到激活毒素基因表達的水平。

Natural competence in streptococcus pneumoniae is regulated by a competence mechanism comsisting of a competence - stimulating kinase receptor ( comd ) and a response regulator ( come ) . the competence is suggested that it can induce the virulence of streptococcus pneumoniae 肺炎鏈球菌( streptococcuspneoumoniae , s . pn )是一種條件致病菌,其條件致病性可能與它在體內發生自然轉化有關,但目前尚未見到研究這方面關系的相關報道。

In the quest to understand and combat infectious diseases and , more recently , to uncover the basis of non - pathogenic microbial colonization , microbes have been found to produce a multitude of factors that either confer virulence or promote colonization by other means 為了了解和戰勝傳染病,尤其是近來為了研究非致病微生物的定植機制, (科學家)發現微生物產生的各種因子一方面與毒性有關,但也可能會促進其定植。

On our conjecture , gene 3a , a highly conserved sequence , may be the determinant of the virulence of fmdv . changes in 3a have been associated with altered host range . a deletion in 3a has been associated with bovine attenuation of fmdv 我們根據已有資料推測, 3a基因可能是口蹄疫病毒的毒力決定簇,它具有高度保守性,其變異和部分缺失對病毒在牛體內的致弱和宿主嗜性發生改變起重要作用。

The results demonstrated that the developed rt - pcr based protocol is a specific , sensitive and rapid diagnostic technique for apmv - 1 infections in different poultry species and can also be used to determinate the virulence of the pathogens 應用該方法對源于各種禽類的67份可疑apmv刁感染的病料樣品進行檢測試驗,結果陽性檢出率為80石,與常規方法檢測的結果本一致。

And all french parents dream of sending their child to an american university . ” his conclusion was that “ the virulence of the press and a portion of the french elites against the united states reflects a certain envy of your brilliant success 他的結論就是“新聞媒體的負面評價以及部分法國精英群體反感美國恰恰反映出他們嫉妒你們的聰明才智所創造出來的成就。

Type 1 pili is the important virulence factors on the e . coli in fection in chicken . through the adhering of pili , e . coli adhered on the epidermic cell of aspiratory tract , which was the first step of invading in host 1型菌毛是雞源致病性大腸桿菌的重要毒力因子,在致病過程中介導細菌吸附于雞呼吸道粘膜上皮細胞完成入侵的第一步。

When the typhus fever had fulfilled its mission of devastation at lowood , it gradually disappeared from thence ; but not till its virulence and the number of its victims had drawn public attention on the school 但是其病毒和犧牲者的數字,引起了公眾對學校的注意,于是人們對這場災禍的根源作了調查,而逐步披露的事實大大激怒了公眾。

Infectivity and virulence of millet culture . the 7 - day - old broomcorn millet culture was bioassayed against m . persicae nymphs by exposing aphids to conidial showers at 9 different concentrations ( 0 . 4 - 50 . 1 conidia / mm2 ) 由此可見,在所測試的因素中,濕度和溫度對黍米培養物產抱的影響最為明顯,而光照影響較小。

The results of both of virulent attack test and 2 - de were paralleled in the following generations , with decrease of virulence of aeromonas hamphila in the former , and deletion of toxin - related genes in latter 攻毒實驗和2 - de的結果均表明在傳代過程中一些毒力相關的因子隨著傳代的進行而逐漸消失。

Result competence can be induced in vitro and the expressing level of three virulence , lyta , nana , hyl , are higher in wild type than in the come mutant 另外還作了comc的表達測定,從基因水平確定感受態的發生。結果s pn在自然條件下轉化時,培養后吸光度到0