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veratridine n.【化學】藜蘆定。

veratrin

Compound pattern ( 6 . 4 % ) , its scatter map of isi series displayed two or more oscillation patterns . 4 . after the bath in 1 . 8 - 3 u mol / l veratridine , touch or pressure on the l5 receptive fields could trigger some primary silent drg neurons to produce high - frequency firing , termed triggered oscillation , whose interspike intervals ( isi ) showed u - type or other types of oscillations 在部分靜息神經元lsdrg浸浴壹蘆堿后,觸壓該神經元的皮膚感受野,可以觸發產生持續數秒至數十秒的高頻放電,在散點圖上,其isi序列形成u字形或彌散形等型式的振蕩,稱之為觸發振蕩。

In present study , single fibre recording in vivo from dorsal root on chronically compressed drg model was used . we analyzed the characters of isi series of oscillation firing of type a neurons induced by veratridine , an inhibitor of inactivation gate of sodium channel . so we can establish a basis for understanding the relationship between the inactivation gate of sodium channel and the firing pattern , so as to explore the relationship between the firing pattern and pain 本研究在大鼠背根節慢性壓迫模型上,利用在體單纖維記錄方法,觀察與分析na通道失活門抑制劑藜蘆堿引起受損背根節a類神經元放電isi序列發生的變化特征,為了解na通道失活門與放電型式的關系以及進一步探索放電時間型式與疼痛的關系奠定基礎。

2 . hi some of the neurons with spontaneous activities , veratridine can transform isi series to oscillation type 在有自發放電的神經元,栗蘆堿可使部分神經元的isi序列轉變為振蕩形式。