x
uploads/vasopressin.jpg

vasopressin n.【生化、醫】血管加壓素,血壓激素。

vasopressor

Since 1980s he has been studying the mechanism of normalization of abnormal blood pressure and the resetting of baroreceptor reflex by acupuncture and somatic nerve stimulation , effects of brain osmoreceptor stimulation on sympathetic nerve discharge and renal activity , the role of vasopressin in body fluid and salt homeostasis , difference in gene expression between hypertensive and normotensive rats , hypertension and cardiac ischemia - induced myocardial remodeling , effect of steroids on the nervous system , etc . with his research achievements , dr . yao was awarded science and technology progress prize sponsored by the state education commission grade a award in 1986 , grade b award in 1995 and by the ministry of health grade b award in 1989 and 1993 , grade a award of guang - hua science and technology prize 1995 , and chinese universities science and technology prize grade b award in 2000 近二十年來,他主要從事針刺和刺激軀體神經對心血管和腎臟活動的調整作用刺激腦內滲透壓感受器引起的交感神經放電和腎臟活動的改變血管升壓素在心血管活動調節和水鹽平衡中的作用原發性高血壓的相關基因高血壓和心肌梗死引起的心肌重構甾體激素對神經系統的影響等。他的科研成果曾獲得國家教委科技進步獎一等獎一項1986年二等獎一項1995年衛生部醫藥衛生科技進步獎二等獎二項1989 1993年光華科技基金獎一等獎一項1995年中國高校科學技術獎二等獎一項2000年。

The expressions of il - 1 receptor type i in mouse brain were widely distributed . and the expressions in mouse pvn and son were significantly enhanced by an intraperitoneal administration of lps or seb ( p < 0 . 05 or 0 . 01 ) . the arginine vasopressin - and oxytocin - containing neurons in the pvn and son also displayed immunofluo - rescence labeling for il - 1 receptor type i F0刀1 ) ; i型il 1受體在正常小鼠腦內的表達很廣泛,與對照組比較, lps或seb引起1型幾l受體在小鼠下丘腦室旁核和視上核中表達顯著增強( o

After i . c . v . 6 - ohda , the c - fos expression of these areas induced by cold stress reduced significantly . 2 ) double staining showed that fos - like immunoreactive positive granules were observed in some vasopressin ( avp ) - immunoreactive positive neurons in paraventricular and supraoptic nuclei , as well as in some tyrosine hydroxylase ( th ) - immunoreactive positive neurons in nts and lc nuclei ( 2 )雙重染色顯示,寒冷應激誘導的fos樣免疫反應陽性顆粒可見于室旁核( pvn )和視上核( son )中的部分加壓素( avp )陽性神經元及孤束核( nts ) 、藍斑( lc )中的部分酪氨酸羥化酶( th )陽性神經元。

The colocalization results implicated that nk3 and vasopressin ( vp ) are in same neurons . and by regulating expressing and releasing of vp , nig can modulate function of the paraventricular nucleus and superoptic nuclei . especially it is closely related to salt and water taste 在室旁核和視上核存在nk3受體與加壓素的雙標神經元,與水鹽代謝有關的神經元在高滲刺激下表達fos ,同時可以激活含nk3受體神經元,提示nk3受體通過調節加壓素釋放參與水鹽代謝和滲透壓的調節。

Immunohistochemistry method was used to observe the temporal and spatial expression of nmdar2 , signal molecules , skeleton proteins and connexins in son neurons and glias ( astrocytes and microglias ) . radioimmunoassay was used to detect vasopressin ( vp ) content in plasma before and after hyperosmotic stimulation . ultrastructure between activated son astrocytes and neurons was observed by double immune - electron - microscopic staining method 應用免疫組織化學方法光鏡下觀察高滲刺激后,大鼠視上核膠質細胞(星形膠質細胞和小膠質細胞)受體( nmdar2 ) 、信號分子、骨架蛋白及縫隙連接蛋白的表達的時空變化;應用放免測定檢測高滲刺激前后血漿中vp含量。

But while it is unlikely that people have a mental , smell - based map of their partners in the way that voles do , there are strong hints that the hormone pair have something to reveal about the nature of human love : among those of man ' s fellow primates that have been studied , monogamous marmosets have higher levels of vasopressin bound in the reward centres of their brains than do non - monogamous rhesus macaques 盡管與田鼠不一樣,人類不太可能有一張基于嗅覺的神經系統伴侶圖譜,但若干線索已有力說明,這兩種荷爾蒙能揭示一些人類戀愛的本質在已被研究過的人類靈長目同伴之中,一夫一妻制小長尾猴的大腦獎賞中樞系統中,抗利尿激素水平較非一夫一妻制的恒河短尾猿高。

The present results indicated that the paraventricular nucleus of the hypothalamus and the supraoptic nucleus might have important roles in neuroimmunomodulation . 2 . following lps or seb was administered intraperitoneally , the expression of pcna of splenic cells and il - 1 receptor type i in pvn and son were observed by using immunocytochemistry in the mice . double fluorescent labeling technique was used to determine the relationship of il - 1 receptor type i co - expressions with arginine vasopressin or oxytocin 二、小鼠腹腔內給予細菌內毒素lps或腸毒素seb ,用免疫組織化學方法觀察了脾臟核增殖抗體及下丘腦室旁核和視上核中1型il 1受體的表達,并采用雙標記技術觀察了1型il刁受體陽性神經元和加壓素及催產素表達的關系。

Methods : hyperosmotic pressure animal model was established by administering 3 % sodium chloride as drinking water to rats or increasing osmotic pressure of the culture medium . osmoregulation positions in the brain , reciprocal projection pathways between the medullary visceral zone ( mvz ) and supraoptic nucleus ( son ) or hypothalamic paraventricular nucleus ( pvn ) , oscillation of intracellular calcium in cultured neurons and astrocytes were studied by means of anti - fos , glial fibrillary acidic protein ( gfap ) , tyrosine hydroxylase ( th ) or vasopressin ( vp ) multiple imrnunohistochemical staining , immuno - electronic microscope , wga - hrp retrogradely tracing and cell culture methods . results : ( 1 ) fos positive neurons within the mvz , parabrachial nuclei , locus ceruleus , pvn , son , subfomical organ increased markedly 方法:通過給予大鼠飲用3氯化鈉或提高培養基滲透壓濃度的方法復制高滲刺激模型,主要采用抗fos 、膠質原纖維酸性蛋白( gfap )和酪氨酸羥化酶( th ) (或加壓素? vp )免疫組織化學多重染色、免疫電鏡、 wga - hrp束路追蹤結合免疫組織化學多重染色、細胞培養等實驗方法,系統觀察了中樞參與滲透壓反射的調控部位、下丘腦視上核( son )神經元? ast超微結構的變化、延髓內臟帶( mvz )和son及下丘腦室旁核( pvn )之間往返投射通路和神經元的性質及其與ast的關系、培養神經元和ast內鈣波的變化。

Immunohistochemical localization of neurokinin b receptor ( nk3 ) in the central nervous system of the mouse and its colocalization with vasopressin ( vp ) objective to examine the localization of neurokinin b receptor ( nk3 ) - like immunoreactivity ( - li ) in the central nervous system of the mouse 一、神經激肽b受體( nk3 )在小鼠中樞神經系統的定位分布及與加壓素( vp ) 、 caba 、阿片受體( mor )的共存關系。 1 、神經激肽b受體( nk3 )在小鼠中樞神經系統的定位分布。

Il - 2 modulates the release of several hypothalamic and pituitary peptides , such as met - enkephalin , 9 - endorphin , prolactin , luteinizing hormone , follicle - stimulating hormone , thyrotropic hormone , growth hormone , adrenocorticotropic hormone , corticotropin releasing factor , arginine vasopressin and somatostain Il - 2通過影響下丘腦-垂體-腎上腺皮質軸的功能,而調節多種下丘腦垂體激素和神經遞質的釋放,如加壓素、乙酰膽堿和去甲腎上腺素等。

The genes studied do n ' t control a specific physical ability , but they dictate two well - known social and behavioral chemicals in the body : serotonin and vasopressin . as researchers suspected , both chemicals were found in much larger quantities among the dancers 結果顯示,這些基因并未控制著一種特殊的身體能力,但是它們卻控制著身體中兩種已知的和社交和行動能力相關的化學物質分別是serotonin和vasopressin 。

The hormones vasopressin ( antidiuretic hormone , or adh ) and oxytocin made in the hypothalamus ( supraoptic and paraventricular nuclei ) are transported into the intra - axonal neurosecretory granules where they are released 下丘腦(視上核和室旁核)形成的血管加壓素(抗利尿激素, adh )和催產素以神經內分泌顆粒的形式經軸突運送至神經垂體得以釋放。

Transcatheter embolotherapy with platinum microcoils and complementary methods including gelatin sponge cubes , surgical glue mixture and intra - arterial infusion of vasopressin were performed 于是使用白金微線圈,和輔助的方法包括凝膠海綿立方體、組織黏膠和淋皮道卵造影液的混合物,以及動脈內升壓劑輸注經導管作栓塞治療。

The results suggest that the hypothalamic pvn and son might participate in neuroimmunomodulation , and partial arginin - vasopressin - and oxytocin - containing neurons in these two nuclei might have a pivotal role 01 ) :在下丘腦室旁核和視上核中1型ili受體陽性的神經元既有加壓素能的,又有催產素能的。

It seems possible , then , that animals which form strong social bonds do so because of the location of their receptors for vasopressin and oxytocin 那么看起來,能形成穩固社會聯結的動物之所以愿意建立彼此間的伙伴關系,可能是由它們的抗利尿激素和催產素受體在大腦中的位置所決定。

Arginine vasopressin ( avp ) is another endogenous fever - reduced peptide , which may acted its antipyretic effect by combining with vsa receptor 精氨酸加壓素( argininevasopressin , avp )也是一種內源性解熱物質,它通過作用于vsa的受體而發揮解熱作用。

The researchers also showed that , as the offspring aged and fathers became detached from them , the abundance of vasopressin receptors fell 研究人員還指出/發現,隨著幼子年齡的增長,父親同他們逐漸疏遠,后葉加壓素受體的數量會有所下降。

Intraarterial vasopressin infusion or embolotheraphy was used after superselective catheterization of the bleeding branch artery 經選擇性插管造影,篩選出出血動脈后,采用同軸導管法超選擇性插管,行血管加壓素灌注治療或栓塞治療。

Inability to suppress as well as to stimulate arginine vasopressin secretion and anesthetic and surgical stresses , were thought to be the possible causes of this event 無法適當的抑制及刺激精氨酸增壓素的分泌應是可能的原因。