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trypanosome n.【動物;動物學】錐蟲屬。

trypanosomiasis

A rabbit was infected with a cloned yntatl , blood was collecting from from the rabbit every 3 days after infection within 30 days , 10 clonal trypanosome populations were gotten , infecting a new rabbit by the last non - cloned trypanosome population . repeated above all , thus infected 5 rabbits sequentially . twenty different vats ( variant antigen type ) were monitored and characterized from those fifty mono - clonal populations by indirect immunofluorescence test ( ift ) and avidin biotin enzyme immunoassay ( abc - eia ) 用伊氏錐蟲云南水牛單克隆株yntat1感染兔,感染后30天內,每3天從兔血中分離錐蟲并單蟲克隆,最后一個未單蟲克隆的蟲株感染另一只兔,重復以上操作,這樣順序感染5只兔子,共獲得50個單克隆錐蟲種群( tp ) ,經間接免疫熒光和abc酶標試驗鑒定共為20個抗原性互不相同的抗原變異體( vats ) 。

Found the phenomenon observed in the nematode caenorhabditis elegans for the first time in 1998 , consequently similar processes have been described for drosophila melanogaster , trypanosome , mammals including humans . the mechanism is that sirnas is the mediator , which can induce the risc to the target mrna and degrade it . recently there was great progress in the specific gene therapy and anti - virus , and rnai has been a focus of rna molecular therapy 自1998年fire等在研究線蟲時首次發現以來,相繼在果蠅、渦蟲、錐蟲、小鼠及哺乳動物細胞中發現rnai現象。一般認為: rnai第四軍醫大學碩士學位論文效應作用機制是sirnaskmallinterferinguaduplex )作為中介分于,引導risc ( rnaiinducingsuppresscomplex )至靶基因m洲a處,隨后核酸內切酶將之降解。

Like the trypanosome ' s vsg coat , the immune system ' s b lymphocytes also express one protein ( immunoglobulin ) on their surface at a time , even though each b cell has many different genes for the surface proteins 一如錐蟲的vsg外套,人體免疫系統的b淋巴球就算擁有許多不同表面蛋白的基因,每回也只表現一種表面蛋白(免疫球蛋白) 。

Three antibody banks were set up depending on 20 vats . some sd rats infected 100 trypanosomes were survived in yuanhun and activing - trypanosome antibody bank treated . vsg - antibody bank was similar to control 我們分離到的vats只有20個并且優勢vats多次重復,這說明在伊氏錐蟲感染兔,波動的vats局限在一定范圍之內。

He proed to be infected by trypanosoma eansi , a trypanosome which is usually a parasite of arious animals , particularly cattle 他被證實感染了伊氏錐蟲,這種錐蟲是一種在各種動物,特別是牛中常見的寄生蟲。

The trypanosome , which branched from other eukaryotes 300 million years ago , breaks this universal rule 在三億年前從其他的真核生物分支出去的錐蟲,卻打破了這條通用的法則。