transferase n.【生物化學】轉移酶。
n. 【生物化學】轉移酶。 “acetyl transferase“ 中文翻譯： 乙酰轉移酶; 轉乙酰酶“acetylglucosaminyl transferase“ 中文翻譯： 乙酰葡糖氨基轉移酶“acetylneuraminyl transferase“ 中文翻譯： 乙酰神經氨酸基轉移酶“adenosine transferase“ 中文翻譯： 腺苷轉移酶“adenyel transferase“ 中文翻譯： 腺苷酰轉移酶“adenylyl transferase“ 中文翻譯： 腺苷酰工轉移酶; 腺苷酰基轉移酶; 腺苷酰轉移酶“alkyl transferase“ 中文翻譯： 烷基轉移酶“amide transferase“ 中文翻譯： 酰胺基轉移酶; 酰胺轉移酶“amidophosphoribosyl transferase“ 中文翻譯： 酰胺磷酸核糖基轉移酶“amino transferase“ 中文翻譯： 氨基轉移酶; 轉氨酶“aminopropyl transferase“ 中文翻譯： 氨丙醇轉移酶; 氨丙基轉移酶“arginyl transferase“ 中文翻譯： 精氨酰基轉移酶“carbamyl transferase“ 中文翻譯： 氨甲酰基轉移酶“carboxyl transferase“ 中文翻譯： 羧基轉移酶“coa-transferase“ 中文翻譯： 輔酶a轉移酶“cyclophosphonucleosidyl transferase“ 中文翻譯： 環磷核糖基轉移酶“cytidylate transferase“ 中文翻譯： 胞苷酸轉移酶“deoxynucleotidyl transferase“ 中文翻譯： 脫氧核苷酸轉移酶“dimethylallyl transferase“ 中文翻譯： 二甲丙烯基轉移酶; 二甲烯丙基轉移酶“dipeptidyl transferase“ 中文翻譯： 二肽基轉移酶“enoylpyruvate transferase“ 中文翻譯： 烯酰丙酮酸轉移酶“farnesyl transferase“ 中文翻譯： 法尼基轉移酶“formimino transferase“ 中文翻譯： 亞胺甲基轉移酶“xylose transferase“ 中文翻譯： 木糖轉移酶“transferase deficiency galactosemia“ 中文翻譯： 轉移酶缺乏性半乳糖血癥“transferarrangement“ 中文翻譯： 橫移軋件用的拖運裝置
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Objective : polypeptide : n - acetylgalactosaminyl transferase is the initiation enzyme catalyzing the linkage of o - glucan chain . recent study shows that o - glucosylation is closely related to molecular recognition , tumor formation , development and metastasis , as well as embryonic development . due to the initial study on function of o - glucosylation in china , this thesis aims to obtain stably expressed pp - galnac - t2 gene clones for further study 目的多肽： n乙酰氨基半乳糖轉移酶是合成o糖鏈的起始酶，而目前的研究認為， o -糖基化與分子及細胞識別、腫瘤的發生發展和轉移以及胚胎發育等功能密切相關。 |
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By yeast two - hybrid assay , aes was found to interact with gp130 intracellular region through its conserved q domain . results from the yeast two - hybrid assay , gluthione s - transferase fusion protein pull - down assay and immuno - co - precipitation assay indicated that the q domain of tle1 is capable of binding gp130 intracellular domain , and the intracellular membrane proximal region of gp130 containing conserved boxl and box2 motifs seemed essential for this interaction . to investigate the consequence of this interaction , tle1 - gfp fusion protein expression vector was constructed and co - transfected into nih 3t3 cells with gp130 expression vector 在通過酵母雙雜交分析確定aes通過q結構域與sp130分子胞漿區結合的基礎上，為確定tle1分子是否也能通過保守的q結構域與gp130分子胞漿區結合，我們通過pcr擴增編碼gp130胞漿區與tleq分子不同結構域的cdna ，構建了含有這些不同結構域的酵母雙雜交載體，通過酵母雙雜交分析證實： tle1分子通過其氨基端的q結構域與gp130分子胞漿區近膜段結合。 |
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This study was to investigate the effects of sulfur dioxide inhalation at different concentrations on some glutathione - related enzymes such as glutathione s - transferase ( gst ) , glucose 6 - phosphate dehydrogenase ( g6pd ) and glutathione reductase ( gred ) in brain , lung , heart , liver , kidney and spleen of mice by the technology of biochemical toxicology . the results were showed as follows , so2 exposure at different concentrations caused the changes of glutathione redox system . moreover , the activities of antioxidative enzymes and the contents of reduced glutathione ( gsh ) were decreased significantly in different tissues at higher concentrations of soa 本研究利用生化毒理學技術研究了不同濃度二氧化硫吸入( 22 2mg m ~ 3 ， 64 3mg m ~ 3 ， 148 23mg m ~ 3 )對純系昆明小鼠腦、肺、心、肝、腎、脾六種組織的谷胱甘肽還原酶( glutathionereductase ， gred ) 、谷胱甘肽硫轉移酶( glutathiones - transferase ， gst )和葡萄糖- 6 -磷酸脫氫酶( glucose6 - phosphmedehydrogenase ， g6pd )活性的影響，結果表明so _ 2吸入使小鼠不同組織的谷胱甘肽氧化還原系統發生了改變，表現為隨著so _ 2吸入濃度的增加，該系統中的抗氧化酶活性的顯著變化和抗氧化物質水平的顯著降低，且存在著組織差異性。 |
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Cotransfected constructed plasimds with pcat3 - control into the hela cell and employed cat ( chloramphenical acetyl transferase ) elisa assays to identified the function of constructed plasmid . the result indicates ie180 mutant p1p2 and p1p3p2 can transactivated the sv40 promoter . the mutant p6p2 repressed to sv40 promoter 與報告質粒pcat3 control共轉染hela細胞，在pcat3 control中含一個sv40真核啟動子帶動著一個報告基因? ?綠酶素乙酸轉移酶（ chloramphenicolacetyltransferase ， cat ） ，它在哺乳動物細胞中能表達cat蛋白。 |
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Recently , the chinese plant protection agencies reported the growing hardships in controlling some field populations of oriental migratory locust with organophosphate ( op ) compounds . up to now there are more than 600 arthropod species with documented resistance to one or more insecticides and / or acaricides since resistance phenomenon was first described in san jose scale to lime - sulfur in washington in 1908 . enhanced metabolic detoxification and reduced sensitivity of insecticide target - sites are the two major mechanisms in resistance development , involving three primary metabolic enzymes of esterases , glutathione s - transferases and cytochrome p450 polysubstrate monooxygenases 代謝抗性是指對殺蟲劑起水解或隔離作用的酶發生改變，從而對殺蟲劑起到解毒作用，昆蟲主要解毒酶系有酯酶、谷胱甘肽- s -轉移酶、細胞色素p450單加氧酶等，這三種酶系任何一種的組成部分發生改變均會引起害蟲抗性的改變；靶標抗性是指由于殺蟲劑作用靶標敏感度降低而產生的抗性。 |
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Cat ( chloramphenical acetyl transferase ) elisa assays to identified the function of constructed plasmid . the result indicates mutant p1p2 , p1p3p2 and p6p2 repressed to cmv promoter . same as ie promoter two special sequences “ atcgt “ located at two side of the transcription initial site of promoter 共轉染hplp細胞，結果表明所有的缺失突變體對cmv啟動子都表現抑制活性，我們發現在ie180和p啟動子的轉錄起始位置兩側同時具有兩個特征序列（ 5 ’ atffit 3 ’ ） 。 |
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Researches of schistosomiasis vaccines have gone more than 60 years , approximately including from the stages of dead vaccine and live vaccine ( irradiated attenuated cercariae vaccine ) to gene engineered vaccine , etc . many different forms of vaccines have been tested in animal models , including gluthathione s - transferase , paramyosin , irv - 5 , triose phosphate isomerase , sm23 , fatty acid binding protein ; which were considered promising by who / tdr . but none of them steadily accomplished the pre - set target level of 40 % protection . in order to enhance the protective capacity further , it is essential to develop novel vaccine antigens and / or vaccine adjuvants 血吸蟲病疫苗研究已有60多年的歷史，大致經歷了死疫苗、活疫苗(照射致弱尾蚴疫苗)和基因工程疫苗等研究階段，產生了一些who / tdr推薦認為很有希望的疫苗候選分子，如谷胱甘肽- s -轉移酶( gst ) 、副肌球蛋白( sm97 ) 、照射致弱疫苗抗原5 ( irv - 5 ) 、磷酸丙糖異構酶( tpi ) 、曼氏血吸蟲膜內在蛋白( sm23 )和脂肪酸結合蛋白( fabp ， sm14 )等，但其對宿主的保護作用均不甚理想，未能穩定地達到40或以上的保護力水平，因此有必要繼續尋找新的疫苗抗原分子和/或疫苗佐劑，進一步提高其保護力。 |
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From the view of cellular rheology , we examined the influence of fluid shear stress on the metabolism , morphology , structure and function of endothelia cells in our previous research . it is first time for us to develop the research between shear stress and apoptosis . in this study , we stimulate the human umbilical venous endothelial cells ( huvec ) by lps and apply different levels of fluid shear stress to them by a parallel plate flow chamber , then observe the change of apoptosis of endothelial cells by terminal deoxynucleotidyl transferase mediated dutp nick end labeling ( tunel ) 我們從細胞力學的角度，曾對血管內皮細胞在剪切力作用下的代謝、形態、結構及功能等進行過系統研究，但剪切力與內皮細胞凋亡的相關研究尚屬首次，我們希望通過探討細胞凋亡與剪切力大小及作用時間的關系，為探索剪切力對血管內皮細胞信號轉導的影響及作用機理提供有價值的參考數據和實驗資料。 |
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Among the genes , there were genes directly related to liver regeneration : fetuin , cathepsin ; close related to liver function : cytoplamic aspartate aminotranferase , gutathion sulfur transferase ; related to substance and energy metabolism : atp synthetase , ribosomal protein , and related to stress response : haptoglobin , transferrin 這些基因中有和肝再生有直接關系的如：胎球蛋白、組織蛋白酶；和肝臟功能密切相關的如：胞質天冬氨酸轉氨酶、谷胱甘肽硫轉移酶；與物質能量代謝有關的如： atp合成酶、核糖體蛋白；以及與急相反應有關的如：觸珠蛋白、轉鐵蛋白。 |
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An expression vector carrying a fragment encoding the amino - terminal part of an fr - 008 type i pks module , containing a keto - synthase ( ks ) and part of an acetyl - transferase ( at ) domain was constructed for trial expression of the extremely high g + c content ( 76 % ) pks gene in plant 為探索在植物中表達極高g + c含量的pks基因的可能性，構建了攜帶有編碼fr - 008型pks模塊氨基端部分的基因的表達質粒，包括一個酮基合酶( ks )和部分酰基轉移酶( at )活性結構域。 |
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2 - e4 and s2 is induced respectively by 8 - ag and 5 - brdu with different drug concentration to make them deficient in hypoxanthine - guanine phosphoribosyl transferase ( hgprt ) and in thymidine kinase ( tk ) respectively and renamed 2 - e4 - a and 82 - 6 . their antibodies “ isotypes are tested by goad anti - mouse isotype regent 取馴化好并處于對數生長期的2 - e _ 4 - a和s _ 2 - b細胞，再常規融合和篩選，三次克隆化后得穩定分泌雙特異性抗體的雜交-雜交瘤細胞株6株。 |
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Investigations were carried to assess the sublethal effects of the insecticides ( fipronil and triazophos ) and the heavy metals ( cd2 + and pb2 + ) on activities of brain acetylcholinesterase ( ache ) , hepatic glutathione - s - transferases ( gst ) and liver esterases in pseudorosbora parva 處理在24h時的抑制率為79 . 5 ，是三唑磷的近4倍、處理iv的1 . 6倍，但在48h后，處理i 、處理iv和三哩磷的抑制率基本接近。 |
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The mechanism of chloramphenicol toxicity is apparently failure of the newborn to conjugate chloramphenicol with glucuronic acid due to inadequate activity of hepatic glucuronyl transferase 氯霉素中毒的機制顯然是由于新生兒肝臟的葡萄糖醛酸轉移酶活性不足，不能使氯霉素與葡萄糖醛酸結合。 |
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The mechanism ofchloramphenicol toxicityis apparently failure of the newborn to conjugate chloramphenicol withglucuronic aciddue toinadequate activityof hepaticglucuronyl transferase 氯霉素中毒的機制顯然是由于新生兒肝臟的葡萄糖醛酸轉移酶活性不足，不能使氯霉素與葡萄糖醛酸結合。 |
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But the ppl researchers have succeeded in knocking out only one copy of the gene for the enzyme , called alpha 1 ， 3 galactosyl transferase 但是, ppl醫療公司的研究人員只是成功地去除了產生這種叫? 1 , 3半乳糖轉移酶的基因的一個副本。 |
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Transferase an enzyme that catalyzes reactions in which entire groups or radicals are transferred from one molecule to another 轉移酶：是一種催化反應物分子的整體結構或基礎部分轉移到另一個分子的酶。 |
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Two expression systems were used , one of which was qiaexpress system , the other glutathione s - transferase ( gst ) gene fusion system )系統和谷胱甘肽s ?轉移酶( gst )基因融合表達系統。 |
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Performance of the chinese hamster ovary cell hypoxanthine guanine phosphoribosyl transferase gene mutation assay 中國倉鼠卵巢細胞次黃質鳥嘌呤轉磷酸核糖基酶基因變異鑒定的操作 |
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Effects of peg stress on gluathione s - transferase activities in the seedlings of common centipede grass eremochloa ophiuroides 聚乙二醇脅迫對假儉草谷胱甘肽轉硫酶活性的影響 |