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thymidine n.【藥學】胸(腺嘧啶脫氧核)苷。

thymine

Pseudorabies virus ( prv ) is the causative agent of aujeszky ' s disease , which results in significant losses in pig husbandry . thymidine kinase ( tk ) gene is one of the main virulent genes of prv , and it is essential to the propagation of prv in the nerve tissues , but dispensable for virus replication and infection in other tissues 偽狂犬病是由偽狂犬病病毒( pseudorabiesvirus , prv )引起的家畜和多種野生動物的一種以發熱、奇癢、呼吸和神經系統疾病為特征的急性傳染病,妊娠母豬可發生死胎和流產,是危害養豬業的一個重要傳染病。

Two spider silk protein genes ( avfl and avf2 ) screened from the library are characterized in a lot of repetitive motifs , a high guanosines or cytidines content , a strong preference for adenosine or thymidine in the third position of a codon and rich residues of glycines or alanines in the proteins translated 試驗結果,該文庫容量為4 . 9 10 ~ 6 。從文庫中篩選到avf1和avf2蛛絲蛋白新基因,具有典型重復序列多, g c含量高,密碼子第三個堿基偏愛使用a t及編碼蛋白中含有大量gly和ala殘基等特點。

The determination of human thymidine kinase ( htk ) in human serum , which is a key indicator of cancers can give information for the diagnosis and treatment of the malign diseases . the protein a layer was first self - assembled onto the gold electrode surfaces of quartz crystals , the monoclonal antibodies were then orientedly immobilized through the specific binding between the fc terminals of the antibodies and the self - assembled protein a . with this sensor , the affinity constant of antigen - antibody binding was estimated to be 1 . 85 106 l / mol according to the scatchard ’ s plotting method , which proved the high bioactivity of antibody . finally , an amplified piezoelectric immunosensor was designed to determine the htk in 實驗中將蛋白a吸附于鍍金壓電石英晶體電極表面,用于定向固定htk單克隆抗體,成功研制了檢測htk的壓電石英晶體傳感器,并基于標準scatchard繪圖法,計算出免疫反應的親和常數為1 . 85 106l / mol ,證明該單克隆抗體具有較高的免疫活性;同時基于酶催化沉淀技術,設計了的檢測htk的質量放大壓電石英晶體傳感器,該傳感器可在0 . 1 - 10ng范圍內對htk進行定量檢測,應用此傳感器成功地對5種癌癥病人血清中htk的濃度進行了測定,實驗結果為癌癥的臨床診斷與治療提供了參考。

2 - e4 and s2 is induced respectively by 8 - ag and 5 - brdu with different drug concentration to make them deficient in hypoxanthine - guanine phosphoribosyl transferase ( hgprt ) and in thymidine kinase ( tk ) respectively and renamed 2 - e4 - a and 82 - 6 . their antibodies “ isotypes are tested by goad anti - mouse isotype regent 取馴化好并處于對數生長期的2 - e _ 4 - a和s _ 2 - b細胞,再常規融合和篩選,三次克隆化后得穩定分泌雙特異性抗體的雜交-雜交瘤細胞株6株。

5 - fu is a inhibitor for purine metabolism and able to suppress various animal tumors . it can suppress thymidine synthetase to affect dna synthesis . in addition , it can also affect rna 化療藥物: 5 - fu為嘧啶類抗代謝藥,對多種動物腫瘤有抑制作用,可抑制胸腺嘧啶脫氧核甘合成镅,影響dna的生物合成,此外,還可以作用于rna 。

We also provide single mono - deoxynucleotide , such as deoxyadenosine monophosphate ( damp ) , deoxycytidine monophosphate ( dcmp ) , thymidine monophosphate disodium ( tmpna2 ) , deoxyguanosine monophosphate disodium ( dgmpna2 ) 我們還提供脫氧腺苷酸,脫氧鳥苷酸二鈉,胸苷酸二鈉,脫氧胸苷酸等的單體

We have identified six conserved domains by multiple sequence alignments of the thymidine kinase proteins of the alphaherpesviruses 通過對皰疹病毒tk氨基酸進行多序列比較,我們獲得了在prvtk氨基酸序列上的六個保守區間。

Mechanism of action : stavudine , a nucleoside analogue of thymidine , inhibits the replication of hiv in human cells in vitro 司他夫定是胸苷核苷類似物,可抑制hiv病毒在人體細胞內的復制。

Construction of an expression system of epstein - barr virus thymidine kinase tk 的克隆及表達載體的構建