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threonine n.【生物化學】蘇氨[胺]酸。

threpsology

Introduction protein kinase c ( pkc ) is a number of serine / threonine kinase family which play central regulatory roles in a multitude of cellular processes , including cell proliferation , cell cycle progression , differentiation , apoptosis . increasing evidence from studies using in vitro and in vivo systems suggests that pkc is a key regulator of critical cell cycle transitions , including cell cycle entry and exit and the gl and g2 checkpoint 前言細胞周期是細胞增殖、分化的一個重要過程,它的啟動與進程受到嚴格調控,參與調控的因子不僅包含起正調控作用的細胞周期素( cyclins ) 、細胞周期蛋白依賴性激酶( cyclin - dependentkinase , cdk ) 、還有起負調控作用的cdk抑制因子( cyclin - dependentkinaseinhibitor , cki ) 。

A combined metabolic mutated strain ( ys - c ) was get by traditional filter method from corynebacterium glutamicum ( ys ) . this mutant is threonine auxotrop , aec and ahv resistant , and it can grow in the medium which contants sca as the only source of carbon , and the mutant can endure hight leveal of leu . the mutanted strain can concentrate lysine . the concentration of lysine leveal was 1 . 20g / l 運用傳統育種手段篩選到谷氨酸棒桿ys的多重代謝突變組合菌株ys - c 。該菌株為蘇氨酸營養缺陷型,具有對賴氨酸的結構類似物aec和ahv的抗性,并且能以琥珀酸為唯一碳源生長,能夠耐受高濃度亮氨酸。

It possess high homology with those of ck2 ( casein kinase 2 ) a subunits from various species . it is now well established that protein kinase ck2 is a pleiotropic and abiquitous serine or threonine kinase , which is highly conserved during evolution . we obtained the complete cdna sequence of ck2 a via 5 “ race 酪蛋白激酶ck2是目前發現的普遍存在于真核生物中的絲氨酸蘇氨酸型蛋白激酶,進化上具有高度的保守性并參與了多種生理功能的調控,因而克隆它的基因具有重要意義。

Protein kinase b is newly found as a serine / threonine protein kinase , it could have widely spread functions in cell cycle regulation . the activation of protein kinase b / akt is thought to be a critical step in the phosphoinositide 3 - kinase pathway which regulates cell growth and differentiation 蛋白激酶c ( proteinkinasec , pkc )和蛋白激酶b ( proteinkinaseb , pkb )同屬于絲蘇氨酸蛋白激酶,廣泛參與細胞的多種生命過程,包括生長、分化、細胞周期調控、細胞凋亡等。

All the subjects were genotyped by pcr - rflp ( polymerase chain reaction - restriction fragment length polymorphism ) at polymorphic sac i site inside the exon 7 of the ahsg gene . this polymorphism involves a nucleotide substitution of c to g at the middle nucleotide of the codon at amino acid position 238 resulting in the replacement of threonine ( acc ) with serine ( agc ) 所有的樣本通過聚合酶鏈式反應?限制性片段長度多態性方法( pcr - rflp )對ahsg基因的第7個外顯子內的sac多態性位點進行基因分型,該多態性位點為238號氨基酸密碼子中間的堿基c到g的替換,使蘇氨酸( thr , acc )變為絲氨酸( ser , agc ) 。

The intracellular domain has four distinct regions : the ram domain , the ankyrin repeats , a transcriptional activator domain ( tad ) and the pest ( proline - , glutamate - , serine - , threonine - rich ) sequence . two nuclear localisation sequences are present prior to and following the ankyrin repeats 釋放的胞內區不經其它信號轉導分子的作用可直接進核,與dna結合蛋白rbp - j相互作用并激活下游基因如果蠅的e ( spl ) ( enhancerofsplit )復合體及哺乳類的hes ( hairyandenhancerofsplit )家族基因。

The substance with antibacteria action obtained from forest frog is made up of alanine , aminoacetic acid , leucine , isoleucine , proline , aminoglutaric acid , threonine , serine , lysine . the substance with antibacteria action is a kind of poly peptide with a micromolecul 純化的林蛙皮膚抗菌活性物質經尿素? sds ? page電泳分析,表現為一條帶,分子量約為6 . 28kda 。

Sorafenib , a novel , oral multi - kinase inhibitor , targets on serine / threonine and receptor tyrosine kinases of the tumor cells and vasculature ; blocks the signal transconduction and inhibits tumor growth 摘要索拉非尼是首個口服多激酶抑制藥,靶向作用于腫瘤細胞和腫瘤血管上的絲氨酸和(或)蘇氨酸及受體酪氨酸激酶,阻斷信號傳導,抑制腫瘤生長。

The kinase catalytic domain is 264 amino acids in length and contains all of 11 conserved subdomains and 15 invariant amino acid residues essential fo r eukaryotic serine / threonine protein kinases 激酶區長264個氨基酸殘基,具有所有11個保守的亞結構域和15個對于真核生物絲氨酸蘇氨酸蛋白激酶所必需的保守的氨基酸殘基。

Pre - clinical studies showed that sorafenib inhibited tumor cell proliferation and angiogenesis by blocking serine / threonine and receptor tyrosine kinases which were inseparable with tumor growth 臨床前研究顯示,索拉非尼作用的2種激酶會影響腫瘤細胞增生及血管生成,而此2種行為為腫瘤生長時所不可或缺。

The vfcpkl has an obvious kinase catalytic domain for ca2 + / calmodulin dependent protein kinases and serine / threonine protein kinases , and a calcium - binding domain like calmodulin Vfcpk1具有明顯的ca ~ ( 2 + )鈣調素依賴蛋白激酶及絲氨酸蘇氨酸蛋白激酶的激酶區以及類似于鈣調素的鈣結合區。

A signal transduction via not only two - component regulatory system but also serine / threonine kinases generally regulates morphological and physiological differentiation in streptomyces 途經雙元件調控系統和絲氨酸蘇氨酸蛋白激酶的信號傳導調控鏈霉菌的形態和生理分化。

L - threonine is a neutral , genetically coded amino acid . it is essential in human nutrition . it is a colorless crystalline amino acid that is derived from the hydrolysis of protein 蘇氨酸是一種由蛋白質水解而成的中性氨基酸,無色晶狀,是人類必需的營養成分。

Threonine an amino acid derived from aspartic acid . it is broken down to form glycine and acetyl coa . isoleucine can be synthesized from threonine 蘇氨酸:由天冬氨酸衍生的一種氨基酸。可分解為甘氨酸和乙酰輔酶a 。還可以用于合成異亮氨酸。

Calcium dependent protein kinases ( cdpks ) are a kind of serine / threonine protein kinases that are only present in plants and some protests 鈣依賴蛋白激酶( cdpks )是一類僅在植物和部分原生生物中存在的絲氨酸蘇氨酸蛋白激酶。

Protein kinase b ( pkb , also named kinase akt ) is newly found as a ser - ine / threonine protein kinase Pkb akt2在卵巢癌、胰腺癌細胞中過表達, pkb akt3在大腦和睪丸中表達。

Introduction wnk ( with no lysine kinase ) kinases belong to a novel serine / threonine protein kinase family 前言wnk激酶是一個新的蛋白激酶家族,是withnolysinekinase的縮寫。

< uk > deamination of threonine by the enzyme threonine deaminase produces - ketobutyrate . < / uk > < uk >蘇氨酸被蘇氨酸脫氨酶脫氨產生-酮丁酸。 < / uk >

Molecular cloning and expression analysis of a serine threonine protein kinase gene in upland cotton 蘇氨酸激酶蛋白基因的克隆與表達分析