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synapsis n.(pl. -ses ) 【生物學】染色體結合;聯合;...

synarthrodial

A decade later these structured synapses formed by immune cells are still generating questions : about how cellular machinery or other forces produce the synaptic architecture , how the architecture , in turn , might regulate cell - to - cell communication , how its malfunction could lead to disease , and even how pathogens might exploit the mechanism to their own advantage 時間過了10年,這種由免疫細胞所形成、結構分明的突觸,仍然不斷帶來新的疑問,例如:是什麼樣的細胞機制或其他力量,造就了這些突觸的構造,而這些構造又是如何調節細胞與細胞之間的溝通;突觸構造的病變將如何引發疾病;還有病原體是否可能利用這種突觸機制,來達成自己的目的等。

The dp induced by 1hz shored a more influence on the ppe ( paired - pulse efficacy ) during the behavior learning than that induced by 5hz , which suggested that 1hz - dp had a stronger relation with presynaptic mechanisms while 5hz - dp had a less with it . in conclusion , the results of our experiment showed that 1hz or 5hz stimulation of dneb could completely reverse the ld - ltp at mf - ca3 synapses Ihz的dp對行為動, 1練期間的ppe ( paired一pulseeffieaey , ppe )的影響較大,提示ihz誘導的dp與突觸前機制的關系更大;而shz的dp對行為訓練期間的ppe的影響較小,提示shz誘導的dp與突觸前機制的關系相對較小。

In this paper the methods of chronically implanting microelectrodes , combined electrophysiology with behavioral learning in vivo , were used to study the effects of low frequency stimulation ( lfs ) of the dorsal norepinephrine bundle ( dneb ) on the learning - dependent long - term potentiation ( ld - ltp ) at the hippocampal mossy fiber synapses onto ca3 pyramidal neurons . paired - pulse technique at the intervals of 75 - ms , 150 - ms and 300 - ms was used as the test stimulation . the results showed as follows : 1 本實驗運用慢性微電極埋植技術和電生理學結合行為學的在體研究方法,以配對脈沖檢測(間隔分別為75ms , 150ms , 300ms )為檢測手段,探查了低頻( 1hz , 5hz )刺激去甲腎上腺素背束( dorsalnorepinephrinebundle , dneb )對大鼠苔蘚纖維- ca3 ( mf - ca3 )突觸上習得性長時程增強( learning - dependentlong - termpotentiation , ld - ltp )及動物行為習得的影響。

At mf - ca3 synapses , different stimulus intensity or interpulse interval resulted in different reactions to paired - pulse , including ppd ( paired - pulse depression , the response to the second pulse is smaller than that to the first one ) and ppf ( paired - pulse facilitation , the response to the second pulse is larger than that to the first one ) 使用不同的檢測強度或不同的配對脈沖時間間隔可在mf - ca3通路上記錄到ppd ( paired - pulsedepression ,即第2脈沖反應小于第1脈沖反應)或ppf ( paired - pulsefacilitation ,即第2脈沖反應大于第1脈沖反應)效應。

6 . at mf - ca3 synapses , both the facilitation ration of ppf and the depression ration of ppd decreased to some degree during the expression of ld - ltp . the result suggested that the expression of ld - ltp at the mf - ca3 synapses may be presynaptic 訓練對照組動物隨著行為的習得, mf一ca3通路出現了習得性ltp ,且不管是ppd或ppf均在mf一ca3習得性ltp形成后出現改變,這提示mf一ca3習得性ltp形成后的表達與突觸前機制有關。

To the group , the pictures were instantly understandable and unequivocal : like the synapses that form the critical junctures between neurons in neural communication networks , the contacts between the immune cells involved organized aggregates of proteins 對這些免疫學者而言,這些影像令人一目了然:就如同在神經溝通的網絡里,突觸成為神經元之間的重要連接點;免疫細胞之間的接觸點,也聚集著結構分明的蛋白質。

Dr tononi believes that the function of these slow waves is to “ downscale ” synapses , reducing their size , chemical activity and electrical activity ? and thus the strength with which they connect their nerve cells together ? all over the brain 托諾尼博士認為這些慢波的功用是削弱突觸,減小它們的尺寸、化學活動和電活動,從而在整個大腦范圍內減弱神經細胞間的聯系。

Functional dyes such as fm1 - 43 and fm4 - 64 are used in nearly all of our experiments to depict which synapses on a given cell or network are functional , as well as providing some index of the synapses ' strengths 像fm1 - 43和fm4 - 64這類功能性染料,幾乎被我們用于進行大部分的實驗,以定位實驗細胞或網絡上的哪些突觸具功能性,同時也為突觸效力提供一個索引。

We now have an elementary grasp of how the vast neuronal networks in our brains develop and atrophy , and how they interconnect via synapses and neurotransmitters such as serotonin and dopamine 現在我們對大腦里這個巨大的神經網絡如何發育以及萎縮已經有了初步的認知,并且了解它們如何通過諸如復合胺和多巴胺之類的神經鍵以及神經傳遞素來進行相互作用。

In rats , the painkiller blocked the brain ' s ability to strengthen connections , or synapses , that ratchet down reward or pleasure , researchers from brown university reported in the journal nature 《自然》刊物上刊登了來自布朗大學的調研者們的報道,該報道稱,止痛藥會阻礙大腦協調機能或神經鍵,影響到對反應及快感的感知,這種觀點純屬無稽之談。

Second , electrical stimulation of these neurons should cause a release of the chemical into synapses , and the chemical should then interact with receptors on postsynaptic cells to produce a biological response 其次,對這些神經原的電激,應釋放出化學物質進入神經鍵,然后這些化學物質和連結神經鍵的細胞上的受容器交互作用,產生生物學的反應。

When the stimulus intensity is a half of the value that induced the largest response of synapses , the paired - pulse stimulation of 75 - ms interval produced a stable ppd while the stimulation of 150 - ms or 300 - ms produced a stable ppf 在1 2最大反應強度為檢測刺激時,間隔為75ms時可產生穩定的ppd ,而間隔為150ms和300ms時則可產生穩定的ppf 。

These molecules are secreted into junctions called synapses , where nerve cells abut one another , and when they have done their job they are absorbed back into the cells that secreted them , a process called re - uptake 這類分子被分泌到神經細胞之間相鄰的突觸連接部位,當它們完成使命后便會通過再吸收作用被吸收回分泌產生了它們的細胞中。

In rats , the painkiller blocked the brain ' s ability to strengthen connections , or synapses , that ratchet down reward or pleasure , researchers from brown university reported in the journal nature 《自然》雜志報道,布朗大學研究人員說,在小鼠體內,嗎啡會阻礙大腦加強神經聯系,即突觸聯系的能力。突觸聯系可以傳遞獎勵與愉悅神經信號。

Observations of the structure of immune synapses immediately spurred researchers to investigate what makes the cellular proteins move to the contact point between the cells and organize themselves into specific patterns 免疫突觸構造的發現,讓研究人員趨之若? ,進而探討促使細胞蛋白移到細胞交會之處并排列成特定樣式的原因。

In contrast , the traditional diffusion is localized in pre - synapses and post - synapses . so from 1980 ' s on , the function of no causes the extensive concern from international and domestic research institutions 內源性no由神經元中一氧化氮合成酶( nnos )產生,由于其脂溶性等特性,能夠彌散到包括突觸和神經元的空間中。

Also , transplanted neural cells had formed synapses to communicate with each other and ultimately the striatum , the portion of the brain dopaminergic cells act on to control movement 同樣,移植的神經細胞已經形成突觸以同其他的神經細胞交流,最終同紋狀體傳遞信號,紋狀體是大腦多巴胺能細胞作用的部分并且控制運動。

Also , transplanted neural cells had formed synapses to communicate with each other and ultimately the striatum , the portion of the brain dopaminergic cells act on to control moement 同樣,移植的神經細胞已經形成突觸以同其他的神經細胞交流,最終同紋狀體傳遞信號,紋狀體是大腦多巴胺能細胞作用的部分并且控制運動。

Glia influence the formation of synapses and help to determine which neural connections get stronger or weaker over time ; such changes are essential to learning and to storing long - term memories 神經膠細胞會影響突觸的形成,也會幫助決定神經連結隨時間而增強或減弱,這種變化是學習與儲存長期記憶所必需的。