protein engineering 【生物化學】蛋白質工程〔通過基因拼接等手段制造新藥或改良...
【生物化學】蛋白質工程〔通過基因拼接等手段制造新藥或改良農產品等〕。 “protein“ 中文翻譯： n. 【化學】朊，蛋白(質)。 “engineering“ 中文翻譯： n. 1.工程(技術)，工程學。 2.開車技術。 3.土 ...“a protein“ 中文翻譯： a蛋白; 蛋白“protein a“ 中文翻譯： a蛋白“protein s“ 中文翻譯： s蛋白:依賴維生素k的血漿蛋白,充當凝血系統中c蛋白的輔助因子“s protein“ 中文翻譯： s蛋白“s-protein“ 中文翻譯： s－蛋白“t protein“ 中文翻譯： t蛋白“t-protein“ 中文翻譯： t-蛋白“engineering“ 中文翻譯： n. 1.工程(技術)，工程學。 2.開車技術。 3.土木工程，工事。 4.操縱，管理。 civil [clectrical, mechanical, mining] engineering 土木[電機，機械，采礦]工程(學)。 aeronautical [marine] engineering 航空[輪機]工程。 the E-Corps 工兵部隊。 engineering geology 工程地質。 engineering science 技術科學。 a key engineering project 關鍵工程。 military engineering 工兵學。 an engineering worker 技工。 field engineering 安裝技術。 rocket engineering 火箭技術。 Nature engineering 天工。 “engineering’s“ 中文翻譯： 技術部門“g-protein regulation protein“ 中文翻譯： g蛋白調節蛋白“protein protein interaction“ 中文翻譯： 蛋白質-蛋白質相互作用; 蛋白質相互作用“protein-protein association“ 中文翻譯： 蛋白質相互結合,蛋白質-蛋白質結合“protein-protein interaction“ 中文翻譯： 蛋白質相互作用,蛋白質-蛋白質相互作用“protein-protein interface“ 中文翻譯： 蛋白質-蛋白質界面“engineering design; engineering project“ 中文翻譯： 工程設計“engineering research; engineering study“ 中文翻譯： 工程研究“sambo engineering sambo engineering“ 中文翻譯： 項目“a myeloma protein“ 中文翻譯： a骨髓瘤蛋白“abnormal protein“ 中文翻譯： 異常蛋白質“acarboxy-protein s“ 中文翻譯： 非羧基-蛋白s“accelerator protein“ 中文翻譯： 促進朊“acceptor protein“ 中文翻譯： 受體蛋白“accessory protein“ 中文翻譯： 輔助蛋白（質）
proteinaceous |
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Air of this advanced development provides efficient methods for protein engineering . in this study , a new two - step procedure has been developed for the detection of cholesterol oxidase activity in streptomyces strains . streptomyces griseus atcc14811 was confirmed to produce cholesterol oxidase and it also showed homologies with the cholesterol oxidase gene ( choa ) from streptomyces sp 本實驗設計了簡單易行的鏈霉菌膽固醇氧化酶活性測定指示平板，結合用鏈霉菌sa - coo ( streptomycessp . strainsa - coo )膽固醇氧化酶基因( choa )為異源探針的southern雜交，確證了灰色鏈霉菌atcc14811 ( streptomycesgriseusatcc14811 )具備產生膽固醇氧化酶的能力。 |
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Mass spectrometry of synthetic hw - ma and rgd - hw are in full agreement with those speculated theoretically , which proves the success of peptide synthesis and refold . on isolated mouse phrenic nerve - diaphragm preparations , hw - ma can block the neuromuscular transmission in 35 minutes or so ( l 10 - 5 g / ml ) , its biological activity shows 73 % decrease comparing with biological activity of native hwtx - i . it proves t hat the protein engineering of synthetic chimera hwtx - i has gained success to some extent , although it did not achieve our expectations . thus it proved that hwtx - i can be using as natural scaffold for protein engineering . and also emphasized the importance of “ local stereo circumstances “ of activity site when the foreign activity site was transferred into a natural scaffold 濃度為1 / 1059 / ml的hw一ma突變體能可逆阻斷小白鼠隔神經書高肌的接頭傳遞，阻斷時一間為35min左右，與天然hwtx一i比較，生物學活性下降3一4倍，說明合成的突變體改造獲得了一定的成功，盡管與我們預期的目標有一定的差距，從而證明hwtx一i可以作為蛋白質工程研究的天然分子骨架，同時也強調了往天然分子骨架中轉移外源活性位點時維持活性位點“局部立體環境”的重要性。 |
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The chinese university of hong kong has entered into a research agreement with genius international holdings limited to develop a technique to produce bone morphogenetic proteins ( bmps ) as a therapeutic device for bone fractures and defects . the new technique will involve the utilization of recombinant dna and protein engineering technology 香港中文大學和雅智國際集團有限公司( geniusinternationalholdingslimited )已達成合作協議，應用基因工程、蛋白工程及生化科學等多學科技術，開發及生產具有成骨生物活性的重組骨蛋白- 2 （ bonemorphogeneticprotein - 2 , bmp - 2 ） ，以應用于治療骨折及骨損傷。 |
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The quest continues for plasminogen activators with higher potency , specific thrombolytic activity , fibrin selectivity and longer half - life time . the recent progress in the protein engineering of plasminogen activators , including t - pa , u - pa , streptokinase , staphylokinase and other novel plasminogen activators , was presented in this article 一些pa突變體及新型溶栓劑，如k2p tnk - pa和star等的臨床實驗結果表明它們在延長體內半壽期增強對血纖維蛋白選擇性和溶栓效率等方面有較大的改進。 |
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In order to prove hwtx - i that can be used as one of natural scaffolds for protein engineering . we have synthesized two multiple mutants : hw - ma and rgd - ma and natural co - conotoxin mviia by using solid phase method with fmoc chemistry on peptide synthesizer and by hand respectively 為了證明hwtx -可以作為蛋白質工程研究的一種天然的骨架分子，本文運用fmoc化學，用手工和固相合成儀合成了兩個hwtx -的多個位點的嵌合體： hw - ma及rgd - hw ，以及合成了天然- conotoxinmviia 。 |
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Modern biotechnology , represented by gene engineering , cell engineering , enzyme engineering , fermentation engineering and protein engineering , is the forefront for scientific innovation in the 21st century . developing ? iological technique and its relevant industry vigorously has become the core of investment and keystone in economic strategy of many countries around the world . a series of preferential policies and regulations have been set down in order to foster and encourage its development 以基因工程、細胞工程、酶工程、發酵工程和蛋白質工程技術為代表的現代生物技術是21世紀世界科技創新的前沿，大力發展生物技術及其產業已成為各國投資發展的核心產業及經濟戰略重點，并制定了一系列優惠的政策和法規，扶植和鼓勵其發展。 |
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The research of the renaturation and biological activity of the chimeras confirmed the active sites of hwtx - i and mviia further . it also indicates that the structure of ick is stable and is an ideal model molecule for protein engineering 通過對嵌合體復性和活性情況的研究，進一步證實了hwrtx一i和mvlla的活性位點;并且表明抑制劑朧氨酸結模體( ick )的結構確實是相當穩定的，是一種進行蛋白質工程的較理想的模型 |
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The space conformation of co - ctx mviia and hwtx - i is highly similar . both molecules contain the typical “ inhibitor cystine knot motif ' ( ick ) , which is a proper molecular model for protein engineering - ctxmv a和hwtx -兩種分子的空間結構十分相似，都包含典型的“抑制劑胱氨酸結模體” ( inhibitorcystineknotmotif ， ick )結構，這是一種適合蛋白質工程改造的分子結構模型。 |
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Protein engineering studies , taking hwtx - i adopting ick structure model as a model molecule , provide important value of basic research and possess a widely applied prospect for other polypeptide neurotoxin according to document reports else 綜合其它文獻報道，以hwtx一i的ick結構模體為分子框架進行蛋白質工程，為其它多膚類毒素提供了重要的基礎研究價值及實際運用前景。 |
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Peking university , national laboratory of protein engineering , beijing , 100871 zhao jianzhou , zhao kuijun institute of plant protection , academy of agricultural sciences , beijing , 100094 北京大學生命科學學院，生物化學及分子生物學系，蛋白質工程國家重點實驗室，北京， 100871 |
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In recent years , a number of rational and combinatorial protein engineering projects have focused on extending and tailoring cal - b ' s catalytic and physical properties 近年來，一系列組合蛋白質工程研究和擴展了南極假絲酵母脂肪酶的催化和物理特性。 |
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Protein engineering and site directed mutagenesis have been used to change the active site and alter the substrate specificity of various hydroxynitrile lyases 研究人員已經利用蛋白質工程和定點突變技術來改變各種醇腈酶的活性位點和底物特異性等。 |
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Department of biochemistry and molecular biology , college of life sciences , peking university national laboratory of protein engineering , beijing , 100871 , china 北京大學生命科學學院，生物化學與分子生物學系蛋白質工程國家重點實驗室，北京， 100871 |
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National laboratory of protein engineering , department of biochemistry and molecular biology , college of life sciences , peking university , beijing , 100871 北京大學生命科學學院，生物化學與分子生物學系，蛋白質工程國家重點實驗室，北京， 100871 |
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The national laboratory of protein engineering and plant genetic engineering , college of life sciences , peking university , beijing , 100871 北京大學生命科學學院，蛋白質工程及植物基因工程國家重點實驗室，北京， 100871 |
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The national laboratory of protein engineering and plant gene engineering , peking university , beijing , 100871 北京大學蛋白質工程及植物基因工程國家重點實驗室，北京， 100871 |
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National laboratory of protein engineering and plant genetic enginnering , peking university , beijing , 100871 北京大學蛋白質工程及植物基因工程國家重點實驗室，北京， 100871 |
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National laboratory of protein engineering and plant gene engineering , peking university , beijing , 100871 北京大學蛋白質工程及植物基因工程國家重點實驗室，北京， 100871 |
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New and highly effective strategies for directed enzyme evolution in vitro have been developed in the protein engineering 酶的體外定向進化是蛋白質工程的新策略。 |