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nucleoside

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nucleoside n.【生物化學】核苷。

n. 【生物化學】核苷。 “adenyl nucleoside“ 中文翻譯：   腺嘌呤核苷“benzimidazole nucleoside“ 中文翻譯：   苯并咪唑核苷“cyclic nucleoside“ 中文翻譯：   環核苷酸“methylated nucleoside“ 中文翻譯：   甲基化核苷“nucleoside analog“ 中文翻譯：   核苷類似物“nucleoside analogue“ 中文翻譯：   核甘類似物“nucleoside analogues“ 中文翻譯：   核甘酸類似物; 核苷類似物“nucleoside antibiotic“ 中文翻譯：   核苷抗生素“nucleoside antibiotics“ 中文翻譯：   核苷抗生素 核苷類抗生素“nucleoside deoxyribosyltransferase“ 中文翻譯：   核苷脫氧核糖轉移酶“nucleoside diphosphatase“ 中文翻譯：   二磷酸核苷酶,核苷二磷酸酯酶; 核苷二磷酸酶“nucleoside diphosphate“ 中文翻譯：   核苷二磷酸,二磷酸核苷“nucleoside diphosphokinase“ 中文翻譯：   二磷酸核苷激酶; 核苷二磷酸激酶“nucleoside hydrolase“ 中文翻譯：   核苷水解酶“nucleoside kinase“ 中文翻譯：   核苷激酶“nucleoside monophosphate“ 中文翻譯：   一磷酸核苷“nucleoside phosphorylase“ 中文翻譯：   核苷磷酸化酶“nucleoside phosphorylases“ 中文翻譯：   核苷磷酸化酶“nucleoside phosphotransferase“ 中文翻譯：   核苷磷酸轉移酶“nucleoside pyrophosphatase“ 中文翻譯：   核苷焦磷酸酶“nucleoside ribosyltransferase“ 中文翻譯：   核苷核糖基轉移酶“nucleoside transdeoxyribosylase“ 中文翻譯：   核苷脫氧核糖轉移酶“nucleoside transribosylase“ 中文翻譯：   核苷核糖轉移酶“nucleoside triphosphate“ 中文翻譯：   核苷三磷酸; 三磷酸核苷“nucleosidase“ 中文翻譯：   核蛋白質分解酵素; 核苷酶; 核甙酶“nucleose“ 中文翻譯：   核？

nucleotide

The nucleoside identity of the genomic sequence of strain f48e9 to that of la sota , v4 , b1 , zj1 and clone 30 strain was found to be 87 . 3 % , 88 . 8 % , 87 . 3 % , 85 . 4 % and 87 . 7 % . on the amino acid sequence level , an identity was 90 . 8 - 99 . 6 % ( np ) , 79 . 5 - 99 . 5 % ( p ) . 89 - 99 . 7 % ( m ) , 87 . 7 - 99 . 8 % ( f ) , 88 . 6 - 99 . 5 % ( hn ) and 92 . 2 - 99 . 6 % ( l ) for this six strain 此外， f48e9株l基因除了編碼一個含有2204個氨基酸多肽外，還可編碼一個52個氨基酸的疏水多肽，而ndv雞源v4 ( hb92 )株和鵝源分離株zj1的l基因不編碼這個小蛋白。

All of our products is exported like nucleotides mix , adenosine monophosphate , cytidine monophosphate , guanosine monophosphate disodium , uridine monophosphate disodium , calcium inosinate , calcium guanylate , calcium 5 - ribonucleotide , damp , dcmp , dgmp , tmp , deoxyadenosine , 2 , 6 - diaminopurine nucleoside , 2 , 6 - diaminopurine deoxynucleoside , adenine arabinoside , adenosine triphosphate , uridine triphosphate , guanosine triphosphate , cytidine triphosphate , cytidine diphosphate choline ( citicoline ) to all over the world , if you are interested in our products , please do visit our website , hope there will fullfill your requirement 主營產品有核苷酸,腺苷酸,胞苷酸,鳥苷酸二鈉,尿苷酸二鈉,肌苷酸,鳥苷酸鈣,核糖核苷酸鈣,脫氧腺苷酸,脫氧胞苷酸,胸苷酸二鈉,脫氧鳥苷酸二鈉,脫氧腺苷, 2 -氨基脫氧腺苷, 2 -氨基腺苷,阿糖腺苷,胞二磷膽堿,腺苷三磷酸,三磷酸尿苷,三磷酸胞苷,三磷酸鳥苷等

It was interested that there was an extra six nucleosides insertion between 1647 - 1652nt ( according to the genomic sequence of la sota strain ) , and the sequence were cccccc in f48e9 strain , and tcccac in zj1 strain . in order to test if insertion of this six nucleosides is related with the virulence of nd , two primers were designed to amplify the same fragment of another ten ndv strains . the result of sequence comparison of 16 strains showed that the six nucleoside was absent in lentogenic strain . this suggested that the six nucleosides insertion might have relationship with the ndv virulence . compared with all known sequence of ndv . there was a special sequence ( 5 ' tctctctcctctctcctcc3 “ ) in the genomic cdna of ndv f48e9 strain 通過rt - pcr方法擴增獲得了另外10個背景清楚毒株的np - p基因間隔區片段，將這些序列與f48e9 、 lasota 、 clone30 、 b1 、 zj1和v4的相應序列進行了比較，結果在參比的16個ndv毒株中在該區段中除了有多個點突變外，個別毒株有堿基插入和缺失，所有以lasota株為代表的弱毒株均無6堿基的插入，而以f48e9株為首的強毒株均有此6堿基的插入，但有一個中等毒力的毒株dp沒有6堿基的插入，不過它的基因序列和lasota的幾乎相同，對于所克隆到的基因的代表性還有待確定。

All of our products is exported likelactobacillus acidophilus , bidifobacterium longum , lactobacillus paracasei , lactobacillus rhamnosus , tagatose , lnulin , nisin , natamycin , - polylysine , nucleotides mix , adenosine monophosphate , cytidine monophosphate , guanosine monophosphate disodium , uridine monophosphate disodium , calcium inosinate , calcium guanylate , calcium 5 - ribonucleotide , damp , dcmp , dgmp , tmp , deoxyadenosine , 2 , 6 - diaminopurine nucleoside , 2 , 6 - diaminopurine deoxynucleoside , adenine arabinoside , adenosine triphosphate , uridine triphosphate , guanosine triphosphate , cytidine triphosphate , cytidine diphosphate choline （ citicoline ） to all over the world , if you are interested in our products , please do visit our website , hope there will fullfill your requirement 主營產品有益生菌（嗜酸乳桿菌、長雙歧桿菌、干酪乳桿菌、鼠李糖乳桿菌） 、塔格糖、菊粉（菊糖） 、乳酸鏈球菌素、納他霉素、 -聚賴氨酸、核苷酸,腺苷酸,胞苷酸,鳥苷酸二鈉,尿苷酸二鈉,肌苷酸,鳥苷酸鈣,核糖核苷酸鈣,脫氧腺苷酸,脫氧胞苷酸,胸苷酸二鈉,脫氧鳥苷酸二鈉,脫氧腺苷, 2 -氨基脫氧腺苷, 2 -氨基腺苷,阿糖腺苷,胞二磷膽堿,腺苷三磷酸,三磷酸尿苷,三磷酸胞苷,三磷酸鳥苷等

Research interests : organic synthesis , including synthetic methodology , divergent oriented organic synthesis , asymmetric synthesis , asymmetric synthesis of small molecules with biological significance ( alkaloids , amino acids , pheromones , nucleosides analogues , enzyme inhibitors , receptor agonists and antagonists , bioactive heterocycles etc ) and chiral drugs 研究興趣：主要從事有機合成化學及相關的化學生物學研究，包括合成方法學、多樣性導向有機合成、不對稱合成、有機小分子調節劑（生物堿，氨基酸，昆蟲信息素，酶抑制劑，受體拮抗劑,核苷類似物等）和手性藥物的不對稱合成。

The fragments were subcloned into a low copy transcription vector ( px8dt ) between the t7 rna polymerase promoter and autocatalytic hepatitis delta virus ribozyme . the result showed that genome of ndv f48e9 strain comprises 15192 nt , which was equal to zjl strain and 6 nucleosides longer than that of la sota , v4 , bl and clone30 實驗結果表明： f48e9全基因組具有15192個堿基，比lasota 、 v4 、 b1和clone30的全基因組序列長6個堿基，和鵝源zj1株的長度相等。

This article reviews the latest progress of nucleoside analogues on the treatment of multiple myeloma in recent years and introduces the mechanism of action , preclinical study and clinical application of fludarabine and gemcitabine in treating multiple myeloma 綜述了近年來核苷類似物治療多發性骨髓瘤的最新研究進展,介紹核苷類似物氟達拉濱和吉西他濱治療多發性骨髓瘤的作用機制、基礎研究和臨床應用。

《 international hepatis 》 ： regarding to nucleoside analogs with hepatitis b antiviral treatment , the drug - resistance raised genetic barriers they , how do you understand genetic resistance barrier ? do you agree 《國際肝病》 ：關于抗乙肝病毒治療的核苷類似物，藥物耐藥性導致基因屏障概念的提出，你如何理解基因耐藥性屏障？你同意這種說法嗎？

Our company is a professional company devoted to continuous innovation in specialty research and development , manufacturing the biochemical products and pharmaceutical intermediates , especially in the field of nucleosides and nucleotrides 我公司是致力于生化產品和醫藥中間體的創新研制及生產的專業公司，特別是在核苷和核苷酸方面。

Q : my first question is if hbv nucleoside analogues happened with the resistance there , then the solution is to add - on other nucleoside drugs for combination therapy , or switch another nucleoside drugs 《國際肝病》 ：乙肝用核苷類似物出現耐藥后，是加用其他核苷類藥物，還是轉換另外一種核苷類藥物？

My first question is if hbv nucleoside analogues happened with the resistance there , then the solution is to add - on other nucleoside drugs for combination therapy , or switch another nucleoside drugs 《國際肝病》 ：乙肝用核苷類似物出現耐藥后，是加用其他核苷類藥物，還是轉換另外一種核苷類藥物？

Prognosis of chronic hepatitis b has been improved significantly because of the clinical application of nucleoside / nucleotide analogues , such as lamivudine , adefovir dipivoxil , entecavir 拉米夫定、阿德福韋酯和恩替卡韋等核苷/核苷酸類似物的臨床應用，大大改善了慢性乙型肝炎的預后。

Q : now the treatment of chronic hepatitis b stress on antiviral treatment , but the nucleoside drugs prone to resistance , what are the consequences once happened resistance 《國際肝病》 ：現在慢乙肝強調抗病毒治療，但核苷類藥物容易出現耐藥，一旦出現耐藥有什么后果？

Now the treatment of chronic hepatitis b stress on antiviral treatment , but the nucleoside drugs prone to resistance , what are the consequences once happened resistance 《國際肝病》 ：現在慢乙肝強調抗病毒治療，但核苷類藥物容易出現耐藥，一旦出現耐藥有什么后果？

Viral dynamic studies showed more rapid decline of serum hbv - dna and eventually viral eradication in combination therapy of two different nucleoside analogues 病毒動力學研究表明：通過兩種不同的核苷類似物聯合治療，血清中的hbv - dna含量會快速下降，最終徹底消除。

Uridine is a white , odorless powder , c9h12n2o6 , which is the nucleoside of uracil , important in carbohydrate metabolism , and used in biochemical experiments 尿苷，白色無味粉末， c9h12n2o6 ，是尿嘧啶中的核苷，在糖類新陳代謝作用中很重要，用于生化實驗中。

Adenosine ( adenine nucleoside ) a nucleoside formed from adenine linked to dribose with a glycosidic bond . adenosine triphosphate ( atp ) is a nucleotide derived from adenosine 腺苷：腺嘌呤與d -核糖以糖苷鍵結合形成的核苷。 atp就是由腺苷中獲得的核苷酸。

Intense analyses of hiv reverse transcriptase have led as well to improved versions of a class of reverse transcriptase inhibitors that do not resemble nucleosides 針對hiv反轉錄酶的深入分析，更產生了一批與核苷類不同但效果更好的反轉錄酶抑制劑。

Nucleoside and nucleotide analogues are usually long - term therapy , potentially life - long , for people with chronic hepatitis b 核甘類似物和核甘酸類似物用作治療慢性乙型肝炎，病人一般需要長期甚至終生接受治療。