x
uploads/neurotoxic.jpg

neurotoxic adj.毒害神經的。

neurotoxin

A neurotoxic peptide ( named huwentoxin - v ) was purified from the venom of the spider by a combination of ion exchange chromatography and reverse phase hplc . hwtx - v has 35 amino acid residues , with the molecular mass 4111 . 4da . the amino acid sequence has been determined as nh2 - ecrwylggcsqdgdcckhlqchsn - yewcvwdgtfs - cooh , which consists of 6 cys , formed three pairs of disulfide bridges 本文報道從虎紋捕鳥蛛( selenocoimahuwena )粗毒中,結合陽離子交換和反相高效液相色譜分離純化出一種昆蟲毒素,命名為虎紋捕鳥蛛毒素- ( huwentoxin - , hwtx - ) ;其天然突變體( themutantofhuwentoxin , mhwtx - )也同時純化出來。

Hwtx - v can reversibly paralyze locusts and cockroaches for several hours with an ed50 value as 16 + 5ug / g to locusts , and larger dose of the toxin can cause death . the neurotoxic symptoms induced by intra - abdominal injection of huwentoxin - v were paralysis , immobilization and last gradually recovery Hwtx -通過腹腔注射,能使蝗蟲和蜚蠊產生可逆的劑量依賴性的麻痹作用,麻痹時間長達十多個小時,在高劑量( 100 g g )時可使蝗蟲和蜚蠊致死,對蝗蟲的ed _ ( 50 ) = 16 5 g g 。

This 40 - residue toxin with molecular weight of 4440 . 18da shows little sequence identity with other spider toxins . another neurotoxic peptide , named huwentoxin - vh , has been purified from the venom of the same spider 此外從虎紋捕鳥蛛( selenocosmiahuwena )毒液中純化的另一種新型膚類神經毒素,虎紋捕鳥蛛毒素一vii ( huwentoxi仆vii , hwtx一vll )的化學性質與基本生物學功能。

Of the three metals studied , mercury is a toxic chemical , particularly in its organic form , which is neurotoxic . inorganic arsenic , a human carcinogen , is the more toxic form of arsenic . cadmium is toxic to the kidney 這項研究所選的三種金屬,汞(水銀)是有毒化學物,尤其是有機汞,可以對神經構成損害;無機砷是砷的有毒形態,是令人致癌的物質;鎘可使腎臟中毒。

Of the three metals studied , mercury is a toxic chemical , particularly in its organic form , which is neurotoxic . inorganic arsenic , a human carcinogen , is the more toxic form of arsenic . cadmium is toxic to the kidney 這項研究所選的三種金屬,汞水銀是有毒化學物,尤其是有機汞,可以對神經構成損害無機砷是砷的有毒形態,是令人致癌的物質鎘可使腎臟中毒。

Parkinson ' s disease arises from genetic and possibly neurotoxic causes that produce massive cell death of the neuromelanin - containing dopaminergic neurons of the substantia nigra 帕金森氏病的病因包括基因突變和神經毒性物質作用,導致黑質多巴胺能神經元大量的死亡。

With its neurotoxic mode of action different from other larvicides , it can be used in rotation with other larvicides to prevent the development of resistance 雙硫磷的滅殺作用模式是令蚊子神經中毒,可和其他不同的滅蚊幼蟲劑輪流使用,防止蚊子產生抗藥

Nucleus pulposus - induced nerve dysfunction may be the result of direct neurotoxic effects , the action of inflammatory agents , or vascular impairment 髓核誘導的神經功能障礙可能是由于直接的神經毒性效應,炎癥反應或血管損害的結果。

The makers of the nerve poison include the mambas and the cobras and their venom is called neurotoxic 產生神經毒液的蛇名叫馬姆伯斯的非洲大毒蛇和眼睛蛇,它們的毒液稱為神經毒素。

The makers of the nerve poison include the mambas and the cobras and their venom is called neurotoxic 產生神經毒液的蛇包括樹眼鏡蛇和眼鏡蛇,它們的毒液稱為神經毒素。

Spider venoms contain a variety of neurotoxic peptide components 蜘蛛毒液中發現有豐富的肽類神經毒素。

Progress of spider neurotoxic peptide 蜘蛛多肽毒素研究進展

“ lts neurotoxic venom is one of nature ' s most effective poisons , “它的神經性毒液是自然界中,

The makers of the nerve poison include the mambas and the cobras and their venom is called neurotoxic . 產生神經毒液的蛇名叫馬姆伯斯的非洲大毒蛇和眼鏡蛇,它們的毒液稱為神經毒素。