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myelin n.【解剖學】髓磷脂。adj.-ic

myelitis

Nogo protein expressed by cns myelin is regarded as a major repulsive factor for the failure of cns axon regeneration . the interest in this protein stems principally from the neurite growth promoting effect of a monoclonal antibody ( in - 1 ) rasied against ni - 250 which has been proved later to be a part of nogo - a 近年來認為髓鞘表達的ni - 250和ni - 35蛋白可能是cns軸突再生失敗的主要因素,用ni - 250作為免疫原制備的單克隆抗體in - 1可識別ni - 250和ni - 35 , in - 1的體內研究結果奠定了ni - 250和ni - 35作為中樞神經再生中最重要的抑制因子的地位。

The red blood cells of a normal person , for instance , age and die in 120 days . new blood cells are formed in bone marrow cells to ensure normal functioning of the human body . however , a vitamin b12 deficiency can make the red blood cells dysfunctional or prevent their successful formation , which in turn causes megaloblastic anemia anemia in which abnormally sized red blood cells are found in the blood . in some cases , prolonged vitamin b12 deficiency can deter the formation and functioning of myelin , subsequently leading to neuritis inflammation of the nerves or incomplete brain development 例如,人類正常的紅血球每120天便會老化死亡,所以骨髓細胞會持續產生新的紅血球,以維持人類正常之身體功能,所以如果缺乏維他命b12 ,便容易造成紅血球生合成功能不全,進而導致巨大型紅血球貧血megaloblastic anemia又例如,因長期缺乏維他命b12 ,會造成神經髓鞘myelin生合成功能不全,進而導致神經炎及腦部發育不全等等。

For example , it plays an important role in the differentiation and growth of various cells , including red blood cells . also , it is necessary for the renewal of epithelial cells and for the maintenance of myelin , the protective coating around the nerves 維他命b12是人體所不可或缺的營養素之一,它對于人體細胞之生長紅血球之形成及上皮epithelium細胞更新及神經髓鞘質myelin之維持扮演著非常重要的角色。

Further experiments revealed that as the healing nerve began to form the protein myelin - the insulating sheath around nerves - this receptor not only caused a reduction in the macrophages ' binding to myelin , but also an outright repulsion from the forming myelin 深入研究揭示,當恢復的神經開始產生蛋白質髓鞘-圍繞神經的絕緣鞘-這種受體不但抑制巨噬細胞與髓鞘的結合,還會直接抑制髓鞘的形成。

When prolactin was injected in non - pregnant mice and the researchers used electron microscopes to examine the results , they were taken aback by how much damaged myelin had been repaired . “ it blew us out of water ” , said dr 研究者將泌乳素注入未妊娠的白鼠體內,以電子顯微鏡觀察其結果,以期確定有多少受損的髓鞘被修復。

One of the major reasons of the failure of cns axon regeneration is the presence of many inhibitory molecules , mostly originated from cns myelin 目前認為cns軸突不能再生的主要因素之一是cns內存在眾多的抑制因子,髓鞘是抑制因子的主要來源。

The typical white matter lesions show loss of myelin and oligodendrocytes , scattered reactive astrocytes , and varying numbers of foamy macrophages 典型的白質病變顯示脫髓鞘、少突膠質細胞、散在的反應性星形細胞,和不同數量的泡沫狀巨噬細胞。

In fact , when the researchers created nerve injury such that new myelin would not be formed , the macrophages continued to lurk around the injury site 實際上,當研究人員(再次)損傷神經,使髓鞘不能形成時,巨噬細胞繼續留在受損位點。

Oligodendrocytes produce myelin insulation , crucial for the transmission of messages around the nerous system 少突細胞設置髓磷脂屏障,這一屏障對神經系統的信息傳導很重要。

The researchers ' experiments also identified specific molecules on myelin that triggered such repulsion 實驗還發現了髓鞘上的觸發這種抑制(作用)的特殊分子。

Impairment of myelin basic protein activated lymphocytes to neurons and its subtype characteristics 髓磷脂蛋白活化淋巴細胞對神經元的攻擊作用及其亞型特點

The myelin project 髓鞘再生研究計劃

Recombinant human brain myelin basic protein and its antibody preparation 重組人腦髓鞘堿性蛋白及其抗體的制備與研究

The myelin has a weblike appearance in such preparations . 髓磷脂在此標本中呈網狀外觀。