x
uploads/mutagen.jpg

mutagen n.【生物學】誘變劑[因素]。adj.adv.-geni...

mutagenesis

Monofunctional alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng ) is a widely spread environmental mutagen and carcinogen that targets dna and proteins to generate adducts . among the adducts , o6 - alkyl guanine is the predominant mutagenic lesion because of its mispairing properties , which can eventually lead to chromosomal aberrations , point mutations , and cell death . this lesion also appears to be involved in tumor initiation , particularly in gastric carcinogenesis 單功能烷化劑n -甲基- n -硝基- n -亞硝基胍( mnng )是一種在環境中廣泛存在的化學誘變劑和致癌劑,它能和dna及蛋白質等生物大分子形成加合物( adduct ) ,其引起的與突變有關的主要dna損傷類型是o ~ 6 -甲基鳥嘌呤,這種損傷與腫瘤尤其是胃癌的發生密切相關。

The paper adopted the common breeding way by series of mutagen treating to the yeast ' s cell and spheroplast . finally , the excellent mutant 75l 3555 was obtained . its nature of the production was determined and it can product ethanol on the condition of 40 and have high fermentative speed and stable production . on the other hand , the test was made that the best fermentative condition was found . in the malt juice , adding 0 . 02 % k + or 0 . 03 % a13 + can increase the production strikingly and adding some degree concentration trahalose can increase the production too and cut short the time of taming . in the study of using molasses producting ethanol , we can obtain high productivity contained the following composition : nitrogen source 1 . 5 % maize and 0 . 075 % ( nh4 ) 2so4 本實驗以常規的育種方法,通過對酵母細胞懸液和原生質體進行一系列誘變,經過大量的篩選,最終選育出一株耐高溫高產菌株75l _ ( 3566 ) ,并對其進行了生產性能的測定。 75l _ ( 3566 )在40條件下,濃度為20 bx的麥芽汁發酵液中,產酒率高達11 . 5 ,而且發酵速度快,發酵周期可縮短12h ,其生產性能穩定,可以適應大部分以淀粉質為原料的生產廠家的需要。同時本實驗對75l _ ( 3566 )進行了發酵條件優化的初步研究。

Streptomyces tenebrarius a04 , the producer ( with a titer of 2874u / ml ) of single component of nebramycin ? apramycin was studied in this paper . after treatment of spore suspension and mycelia shivered by supersonic with mutagen , combined with the application of screening models , some stable high yield apramycin - producing strains ( with a fermentation titer of 4800 - 5200u / ml by shaking flask ) such as a2 - 23 , a2 - 30 , asm6 and al - 16 were obtained 本文以尼拉霉素單一組分?安普霉素產生菌s . tenebrariusa04 (發酵單位為2847u ml )為出發菌株,通過對單孢子懸液和超聲波破碎菌體的誘變處理并復合篩選模型,獲得了遺傳特性穩定的單組分高產菌株: a2 - 23 、 a2 - 30 、 asm6 、 a1 - 16 ,搖瓶發酵單位達4800 - 5200u ml 。

Through a series of mutagen tests , a mutant strain of monascus spp ( m 12 - 69 ) from ml2 was acquired , which can produce much higher monacolin k than m12 , and almost same citrinin level as m12 以之為出發菌株,通過誘變篩選,獲得一株monacolink產率有明顯提高而桔霉素產率僅為0 . 13ng g ( elisa )的突變株,編號為m12 - 69 。

The paper mainly deals with the chromosome doubling method and mutagen types for medicinal plants and other factors affecting chromosome doubling 本文著重介紹了當前藥用植物染色體加倍所采用的方法、誘變劑類型以及其它一些影響植物染色體加倍的因素。

Insertional mutagenesis is a method for identifying genes by using the integration of dna as the mutagen , thereby facilitating the cloning of the mutated gene 插入突變是一種通過外源dna整合的方式來獲得突變體,并克隆得到對應突變基因的方法。

Many constituents are mutagens and carcinogenic such as alkenes , nitrosamines , polynuclear aromatic and heterocyclic hydrocarbons , amines 煙草的很多成分都會引起有機體突變以及致癌,如烯烴化合物,亞硝胺,多核芳香烴以及多環碳氫化合物和銨

However , environmental mutagens can also induce mutations at undamaged sites and result in the so - called nontargeted mutagenesis 但是環境誘變劑引起的突變也可發生在非dna損傷部位,它被稱之為非定標性突變( nontargetedmutagenesis ) 。

Environmental mutagens can also induce mutations at undamaged sites and result in the so - called nontargeted mutation 環境誘變劑引起的突變也可發生在非dna損傷部位,我們稱之為非定標性突變( nontargetedmutagenesis ) 。

Similarly , the cellular response to the environmental mutagens is not always initiated by dna damage 同樣地,環境誘變劑誘發的細胞應答反應也不只是單純地由dna損傷所觸發的。

Study on removing dietary mutagen by antimutagenic lactic acid bacteria 抗突變活性乳酸菌對膳食中誘變劑去除作用研究進展

Methods for disposing mutagens , teratogens and carcinogens 致突變物,致畸物和致癌物的處理方法

Methods for disposing mutagens , teratogens and carcinogens 致突變物致畸物和致癌物的處理方法

Mutagtnic effect of some new mutagens on rice 幾種新的誘變因素對水稻的誘變效應

New variants of some plant viruses have been produced artificially in the laboratory by treating pure virus strains with mutagens . 用亞硝酸之類的誘變處理純病毒株系,能在實驗室內人為地使有些植物病毒產生新變種。