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monocyte

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monocyte n.【生物學】單核細胞,單核白血球。adj.-cytic...

n. 【生物學】單核細胞,單核白血球。 adj. -cytic “adult monocyte“ 中文翻譯：   成人單核細胞“blood monocyte“ 中文翻譯：   血單核細胞“histogenic monocyte“ 中文翻譯：   組織性單核細胞“juvenile monocyte“ 中文翻譯：   幼單核細胞“mature monocyte“ 中文翻譯：   成熟單核細胞“mon monocyte“ 中文翻譯：   單核細胞“mono-monocyte“ 中文翻譯：   單核細胞“monocyte and phagocyte“ 中文翻譯：   單核細胞及巨噬細胞“monocyte chemotaxis“ 中文翻譯：   單核細胞趨化性“monocyte maturation“ 中文翻譯：   單核細胞成熟“monocyte production“ 中文翻譯：   單核細胞產生“monocyte series“ 中文翻譯：   單核細胞系“monocyte-granulocyte“ 中文翻譯：   單核細胞-粒細胞“rosette of monocyte“ 中文翻譯：   單核白細胞玫瑰花狀簇“young monocyte“ 中文翻譯：   幼單核細胞“abnormal monocyte maturation“ 中文翻譯：   異常單核細胞成熟“abnormal monocyte production“ 中文翻譯：   異常單核細胞產生“chemotactic factor for monocyte“ 中文翻譯：   單核細胞趨化因子“circulating monocyte pool“ 中文翻譯：   循環單核細胞池“defective monocyte chemotaxis“ 中文翻譯：   單核細胞趨化性缺陷“in vitro monocyte lysozyme production“ 中文翻譯：   體外單核細胞溶菌酶的產生“lymphocyte-monocyte index“ 中文翻譯：   淋巴細胞單核細胞指數“marginal monocyte pool“ 中文翻譯：   邊緣單核細胞池“monocyte chemotactic factor“ 中文翻譯：   單核細胞趨化因子“monocytangina“ 中文翻譯：   單核細胞性咽峽炎“monocystis epithelialis“ 中文翻譯：   上皮性單囊胞蟲

monodist

Cd 14 * monocytes or bone marrow derived hematopoietic progenitor cells cultured with granulocyte - macrophage colony - stimulating factor ( gm - csf ) and il - 4 differentiate into efficient apc with morphology and cell surface molecule expression typical of immature dc . it was demonstrated that a variety of factors ( such as lps , tnf - a , il - 1 , monocyte - conditioned medium , and cd40 receptor cross - linking ) induce the maturation of immature dc to mature dc that are much more potent in activating t cells by increasing the expression of costimulatory molecules and cytokines , promoting the migration of dc to draining lymph nodes , and down - regulating the capacity of dc to capture and process antigen 在體外，外周血cd14 ~ +單核細胞和cd34 ~ +骨髓造血前體細胞在粒細胞-巨噬細胞集落刺激因子( granulocyte - macrophagecolony - stimulatingfactor , gm - csf )和il - 4的共同作用下可分化為未成熟dc ，未成熟dc具有強大的攝取和處理抗原的能力，但其抗原提呈能力較弱；未成熟dc在炎性細胞因浙江大竿俗士學位論文潛廷平子汐ilq ， yfax病原成分汐lpsx單核細胞條件培養液或cd40l等作用下可分化為成熟dc 。

Conclusion : dendritic cells ( dcs ) can be derived from peripheral blood monocytes in vitro successfully treated with rhgm - csf of 1000 u / ml plus il - 4 of 500 u / ml . second , dcs from the patients of advanced carcinoma of large intestine were transfected with rv - cea , and then cocultured with autologous t cells . the cytotoxic activity against cea - secreting tumor cells were assessed and compared with those of t cells induced by dcs without rv - cea transfection 其次，用rv - cea轉染晚期大腸癌患者的dc ，再激發自體t細胞，然后檢測t細胞對cea分泌性腫瘤細胞的體外殺傷活性，并與未經rv - cea轉染的dc激發的t細胞及野生型痘苗病毒轉染的dc激發的t細胞進行對比。

The optimum concentration of superoxide anions , which resulted in the maximal proliferative effect of mice bone marrow cells , was 1 . 8 - 1 . 9nmol / h / 106cells . superoxide anions also can cause lymphocytes proliferation and it increases with the increasement of monocytes . conclusion : superoxide anions play an important role in the proliferative effect caused by low level radiation and in the proliferation of peripheral blood lymphocytes cultured with monocytes 結論： o _ 2 ~ -在低水平輻射所致小鼠骨髓細胞增殖刺激效應中起關鍵作用； o _ 2 ~ -濃度的升高是淋巴細胞和單核細胞共培養體系中促進淋巴細胞增殖的重要因素。

Conclusion one mechanism of wmt on aso may be its inhibition on arteriosclerosis by way of downregulating the expression of vascular endothelial cells adhesion molecules to decrease the adhesion of monocyte to vec , therefore to inhibit the monocytes migrating into vascular intima to develop foam cells . 2007 vol 結論下調血管內皮細胞黏附分子的表達，減少單核細胞與內皮細胞的黏附，從而抑制單核細胞遷移至血管內膜形成泡沫細胞，抑制動脈粥樣硬化as的形成，可能是溫脈通治療aso的機制之一。

Methods serums containing whole wmt and its disassembled formulas , including the formula consisted of warming jing and boosting qi part wenjin yiqi , wy and that of promoting blood circulation part huoxue tongmai , ht , as well as the serum contained high concentration of lipids were prepared conventionally , respectively . the adhesion of monocytes cell strain thp1 to human umbilical vascular endothelial cells huvec was determined by rose bengal stain method , and elisa was used to detect expressions of intercellular adhesion molecule icam1 , vascular cellular adhesion molecule vcam1 and p selectin on huvec surface 方法常規制備溫脈通全方溫經益氣拆方活血通脈拆方含藥血清和高脂血清，采用虎紅染色法檢測藥物血清對高脂誘導的人臍靜脈內皮細胞huvec和單核細胞株thp1黏附的作用用細胞elisa法檢測huvec表面細胞間黏附分子1 icam1血管細胞黏附分子1 vcam1 p選擇素pselectin的表達。

Conclusion one mechanism of wmt on aso may be its inhibition on arteriosclerosis by way of downregulating the expression of vascular endothelial cells adhesion molecules to decrease the adhesion of monocyte to vec , therefore to inhibit the monocytes migrating into vascular intima to develop foam cells 結論下調血管內皮細胞黏附分子的表達，減少單核細胞與內皮細胞的黏附，從而抑制單核細胞遷移至血管內膜形成泡沫細胞，抑制動脈粥樣硬化as的形成，可能是溫脈通治療aso的機制之一。

We found nuclear deformation lymphocytes with increased heterochromatin and impaired thymus epithelium cells with increased lysosomes and deformation of mitochondrias . ( 4 ) effects on mouse liver of so2 challenge : so2 can cause significant liver injury . he staining showed several kinds of necrosis of liver including spot necrosis , focal necrosis and submassive necrosis infiltrated with lymphocytes , monocytes , few neutrophils and eosinophils ; tem observation showed fatty degeneration with dispersion of fatty droplets and dilation of rough endoplasmic reticulums , acid degeneration with significant hyperplasia of mitochondrias , necrosis of hepatocytes with karyorrhexis and other organelles losing their normal structure ( 4 )二氧化硫染毒對小鼠肝臟的組織學結構有明顯影響，可引起肝臟點狀壞死、灶狀壞死甚至片狀壞死，伴隨不同程度的炎性細胞浸潤；透射電鏡觀察發現二氧化硫可引起肝細胞脂肪變性、嗜酸性顆粒變和壞死，脂肪變肝細胞中可見大小不等的脂滴存在，嗜酸性顆粒變肝細胞中可見線粒體明顯增生，壞死肝細胞可見細胞核結構破壞，細胞器減少，細胞膜不完整。

Lymphocytes and monocytes were isolated from human peripheral blood , then the lymphocytes were cultured with different amounts of monocytes , the ability of lymphocytes proliferation and the concentration of o2were measured by above methods . we added dpi into culture medium to depress the activity of nadph oxidase , which produces superoxide anions , to observe the change of the cell proliferation . results : in a certain concentratin range , the proliferation ability of mice bone marrow cells increase with the increasement of superoxide anions 結果：在一定的濃度范圍內，小鼠骨髓細胞的增殖能力隨) o _ 2 ~ -濃度的增加而增加，在本實驗條件下使小鼠骨髓細胞達到最大增殖效應的最佳o _ 2 ~ -濃度范圍為1 . 8 1 . 9nmol h 10 ~ 6細胞；人外周血淋巴細胞培養體系中加入單核細胞共同培養，可上調介質中o _ 2 ~ -的濃度，從而促進淋巴細胞增殖。

Surface markers on dcs were then analyzed by flow cytometry and the proliferation of t cells was detected by mtt colorimetry . resoults : peripheral blood monocytes from patients of carcinoma treated with rhgm - csf of 1000 u / ml plus il - 4 of 500 u / ml for 7 days could observe dcs with typical morphology . simultaneously there was a decrease in cd 14 expression and increase in hla - dr , cd40 , cd83 and cd86 on dcs 結果，癌癥患者外周血中的單核細胞在rhgm - csf1000u ml + il - 4500u ml的條件下培養一周，就可看到典型的樹突狀細胞形態，其表面cd14分子表達減少， hla - dr 、 cd54 、 cd40 、 cd83及cd86分子的表達明顯增高，且具有明顯刺激t細胞增殖的能力，成功地完成了外周血單核細胞來源的dc的培養。

Hla - g1 , which is a newly defined non - classical hla class i molecule , plays an important role in mediating immunotolerance and protecting embryo and even some kinds of tumors from nk cells attacking . the full - length coding sequences containing cdna of hla - g1 were cloned from placenta , monocytes and liver cancer tissue of chinese donors . sequence analysis reveals that it is a highly conserved human gene with only two amino acid mutation sites compared to foreign nationality . its truncated form was overexpressed in 從中國人外周血單個核細胞胎盤組織和肝癌組織等樣品中克隆了包含完整hla - g1讀框的cdna與國外同行獲得的該基因及其蛋白質序列比較分析表明，該基因雖然有著細微的種族特異性，但高度保守并獲得了它的截斷型重組蛋白，根據蛋白一級結構和同源比較方法，模建了它及其與特異性受體kir2dl4形成復合體的空間結構模擬，預測了它們之間相互作用的特征。

Hi our study , dendritic cells ( dcs ) were derived from the cultivation of peripheral blood monocytes in vitro successfully . then to observe whether dcs transfected with carcinoembryonic antigen ( cea ) - vaccinia recombinant virus ( rv - cea ) can induces cytotoxic t lymphocyte - mediated cea - specific immunity in vitro 體外成功地完成了cd14 +單核細胞來源的樹突狀細胞( dc )的培養，并進一步研究人癌胚抗原重組痘苗病毒( rv - cea )轉染dc后體外誘導的cea特異性細胞免疫。

Except the incomplete maturation of spermatid nuclear and oocyte activation , idendification of a live spermatid is a pivotal procedure . it is difficult to distinguish round spermatids from other round cells such as spermatocytes , monocytes , polymorphonuclear leukocytes and so on 除精子細胞的核蛋白不完全成熟及卵子激活不足等因素外，如何正確選擇存活精子細胞是個難題，如圓形精子細胞與精母細胞、單核細胞和多形核白細胞等其他圓形細胞的區分就比較困難。

Tumor necrosis factor ( tnf ) , a cytkine that exerts many pro - atherosclerotic effects in vivo , causes up - regulation of acat - 1 gene expression in human blood monocytes . by luciferase activity assay , tnf - a enhanced acat - 1 p7 promoter activity in thp - 1 monocytic cell line 細胞因子tnf -即腫瘤壞死因子大量存在于人動脈粥樣硬化斑塊中，本實驗通過熒光素酶活性和rt - pcr測定結果表明， tnf -處理人血單核細胞和單核細胞株thp - 1均增強acat - 1基因p7啟動子活性。

According to the smears from 100 cases of mumps and other 50 cases of bacteria parotitis and / or normal parotid as control , the author revealed that if there are a lot of ductal epithelial cells , monocytes and polynuclear phagocytes at same time , it could give diagnosis “ mumps “ to that patient 經過100名流腮病員和20名細菌性腮腺炎及30名正常腮腺作為對照后發現：若涂片中同時存在多量導管上皮細胞、單核細胞及多核巨噬細胞時即可診斷為流腮。

Yet another subset of macrophages in lung lavage appear smaller than the normal pulmonary macrophage and may be immature , perhaps due to the premature release of monocyte precursors from the bone marrow and homing to the lungs in response to cigarette smoke 當然在肺部灌洗液中也有其他亞型的巨噬細胞體積較正常肺巨噬細胞的小，而且還可能處于幼稚階段，可能與骨髓單核細胞前體物質過早釋放并對吸煙產生反應而游走至肺部有關。

Objective to study the effect of wenmaitong and its disassembled formulas on the adhesion of monocytes to endothelial cells induced by hyperlipidemic serum to explore the mechanism of wmt on early arteriosclerosis obliterans . methods serums . . 目的研究溫脈通及其拆方對高脂血清誘導的單核細胞與血管內皮細胞黏附及黏附分子表達的影響，以探討溫脈通治療早期動脈硬化閉塞癥aso的機制。

Objective to study the effect of wenmaitong and its disassembled formulas on the adhesion of monocytes to endothelial cells induced by hyperlipidemic serum to explore the mechanism of wmt on early arteriosclerosis obliterans 目的研究溫脈通及其拆方對高脂血清誘導的單核細胞與血管內皮細胞黏附及黏附分子表達的影響，以探討溫脈通治療早期動脈硬化閉塞癥aso的機制。

( 5 ) cu amino acid chelate increased mice ' s serum igg content and monocyte phagocytosis , monocyte phagocytosis increased by dietary supplemental copper , and serum igg content increased significantly （ 5 ）氨基酸贅合銅有提高小鼠血清igg含量和單核細胞吞噬功能的趨勢，飼糧中添加銅可提高小鼠單核細胞吞噬功能，并顯著提高血清！

Mid cells may include less frequently occurring and rare cells correlating to monocytes , eosinophils , basophils , blasts and other precursor white cells 中間細胞可能包括與單核細胞、嗜酸性粒細胞、嗜堿性粒細胞、原幼細胞和其他其它前體白色細胞有關的不常見的、稀有的細胞。