H - homologue 中文 - EN166

homologue n.1.【化學】同系物。2.【生物學】(細胞)同源染色體...

homology
Part 1 : identification of a novel gene , tsarg2 , and its sequence character cloning new apoptosis - related novel gene is a key to further understanding of apoptosis mechanism and the biological process of germ cell , and it is of momentous significance on clarifying physiology and pathology process of spermatogenesis . to rapidly attain human novel gene full - length cdna sequence , the gene - specific primers and the vector - specific primers have been designed for successful performing nested pcr and draft human genome searching to rapidly identify the tsarg2 ( genebank accession number ay040204 ) 5 “ end from a human testis cdna library by using a cdna fragment ( genebank accession number be644542 ) as a electronic probe , which was significantly changed in cryptorchidism and represents a novel gene . furthermore , a mouse homologue of this gene was identified ( genebank accession number af395083 ) by lab on - line 本研究分為三個部分，其主要實驗方法及實驗結果如下：第一章tsarg2基因的克隆與序列分析從已獲得的在隱睪和正常睪丸對照中表達量有明顯差異的est片段( be644542 )入手，設計了基因特異性引物和載體特異性引物進行巢式pcr擴增，結合人類基因組草圖搜索法，從睪丸cdna文庫中快速分離出人類睪丸凋亡相關基因的5末端而獲得全長cdna ， genbank登錄號為ay040204 ，同時應用生物信息學的方法克隆了該基因在小鼠中的同源基因， genbank登錄號為af395083 。
In addition , axud1 has a high homologue with transforming growth facotr beta ( tgf - ) induced apoptosis protein 2 and 12 using blast exploration at genebank database . these suggest that axudl may have a tumor - suppressor function in these organs and may play an important role in tgf - - induced apoptosis 通過genkbank上blast的搜索結果表明， axud1與tgf -誘導的凋亡蛋白2 、 12 ( taip - 2 、 taip - 12有較高的同源性，提示axud1可能是一個具有腫瘤抑制功能的基因，并可能在tgf -誘導的細胞凋亡中起著重要作用。
The homology of the other two motifs ( v and vi ) , which are also quite conserved in other helicases , were lower than 30 % . the hasn pv helicase protein had considerable amino acid sequence similarity with other baulovirus helicases ( 58 % ) , and the highest ( 66 % ) with semnpv and the lowest with xcgv . ( 43 % ) . hasnpv helicase was the first helicase reported in single - nucleocapsid nucleopolyhedrovirus there are 5 homologue regions ( hrs ) in hasnpv genome which may play important roles in the viral replication 同源性比較發現hasnpv解螺旋酶的氨基酸序列與甜菜夜蛾核多角體病毒( spodopteraexiguemnpv ， semnpv )的解螺旋酶具有最高的同源性( 66 ) ，與xestiac - nigrum顆粒體病毒( xcgv )解螺旋酶同源性最低( 43 ) ， hasnpv解螺旋酶基因是第一個報道的單粒包埋核多角體病毒的解螺旋酶基因。
The dna sequence had a complete orf ( open reading frame ) , which coded a protein of 479 amino acid residues . the protein sequence of enolase which contained the conserved domain , was homologue to enolase of other organisms . it showed 83 % ideaity and 89 % similarity compared to the enolase in chlamydomonas reinhardtii 并將其中的一個gus基因用目的片段烯醇酶基因替換，構建了可以在植物中高效表達的載體pcambia2301g一enolase ，成功地將其轉入根癌農桿菌eha105中，為下一步進行轉基因植物的研究作準備。
However , only a few host factors with clear in vivo function have been identified . by using pcr and 5 “ and 3 “ race , we were able to clone a homologue ( named ttom1 ) of arabdopsis thaliania host factor gene , tom1 , which supports the replication of tobacco mosaic virus 根據從擬南芥中已經克隆的支持煙草花葉病毒復制的基因tom1序列設計一對特異性引物，用rt - pcr的方法獲得番茄同源基因的部分序列，然后利用5 ’ race與3 ’ race方法從番茄中克隆出全長ttom1基因。
Mint ( msx2 - interacting nuclear target protein ) can interact with rbp - j and msx2 ( the murine homologue of drosophlia muscle - segment homeobox ) , and represses their transcription activation activity 進一步的研究表明mint可以與n成ch受體的胞內段競爭結合rbp j ， n而抑制rbp刁的轉錄激活作用。
The cellular homologue of v - src is c - src , and its protein product c - src is located in the cytoplasm with 60kd 隨后在真核細胞中也找到了同源性的c - src蛋白，分子量為60kd ，位于細胞的胞質中。
Cloning and sequencing analysis of sus scrofa hepatitis c virus core - binding protein 6 homologue gene 豬丙型肝炎病毒核心蛋白結合蛋白6同源基因的克隆化研究
Cloning and sequence analysis of bos taurus hepatitis c virus core - binding protein 6 homologue gene 牛丙型肝炎病毒核心蛋白結合蛋白6同源基因的克隆化研究
A study on the combined estrogenic effects of the isomers and the homologue of ddt pesticide 類農藥同分異構體和同系物的聯合雌激素效應