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endometrium n.【解剖學】子宮內膜。

endomixis

However , there are limitied documents about receptor signal transduction within uterine endometrium during implantation . the factors regulating endometrial receptivity remain poorly understood . the objective of this dessert is to investigate mapk ' s expression and location in differnt days of pregnancy , as more important , we try to elucidate the relation of mapk and the receptivity of endometrium 本課題組經研究還發現lewis ~ y寡糖在植入中呈階段特異性表達,可影響其他如lif 、 egf 、 fn (纖連蛋白)和mmps (基質金屬蛋白酶)等因子的表達,推測其可能作為一種信息分子經某種轉導途徑(例如mapk )而發揮作用。

Most of mapk upstream molecules are the molecular marker of the receptivity of endometrium during implantation period , for instance , evidence suggests egf and its receptor egfr may play a role in rendering the endometrium receptive to embryo implantation . the temporal and spatial expression of ley oligosaccharide in the uterus suggests that this factor may be involved in cell - cell communication between the uterus and blastocyst during implantation period 在植入期的子宮內膜, mapks的上游信號分子大多是其接受態的標志分子,如egf及其受體egfr ,可作為胚泡與子宮內膜間的信息傳遞物質,代替雌激素促進子宮上皮細胞分化、增生,誘導胚胎著床。

Samples were taken from nonpregnant , pregnant and cultured endometrium cell , with using immunohistochemical staining , western - blot methods . to better understand this interaction , we further characterized the expression patterns of egfr messenger rnas in the mouse uterus on days 1 to 8 of pregnancy . in the present study , we found : two isofonns of non - phospho mapk was generally equally expressed in the nonpregnant and pregnant mice endometrium , and little difference among them 本研究以未孕及早孕小鼠( d1 ? d8 )的子宮內膜和培養的d4子宮內膜為樣品,應用免疫組織化學、 western - blot等方法,檢測了小鼠胚胎植入前后子宮內膜erk1 / erk2的表達部位及水平;用rt - pcr方法檢測了egf及其受體egfr的表達情況;對培養的d4子宮內膜以le ~ y寡糖抗體阻斷,觀察了其對活性型mapk表達的影響。

These interactions are primarily dependent upon the coordinated actions of ovarian progesterone and estrogen , moreover , many other factors , such as growth factors , cytokines , ecm , adhension molecules , oligosaccharides and proteases , regarded as local mediators , endometrium and embryo have also expressed some specific receptors , via intracellular signal transduction chains and express some key genes , making receptivity of the uterus and synchronized development of the embryo to the blastocyst stage 成功的植入是處于接受態的子宮內膜和具有侵入性的胚胎間的同步協調反應。植入過程受多種生長因子及其受體、細胞因子、粘附分子、蛋白水解酶、寡糖等的精細調控,通過胞內信號轉導及關鍵基因的表達使子宮內膜發生一系列復雜變化。

Similarly for the obese higher rates of cancer of the breast , colon , ovary , prostrate , endometrium ( the layer of tissue that lines the uterus ) , kidney and gallbladder are all being evidenced now in china and in younger patients than previously observed 同樣,乳腺癌、結腸癌、卵巢癌、前列腺癌、子宮內膜癌(子宮內的一層組織) 、腎癌和膽囊癌在中國的發病率也明顯上升,而且與先前的觀測結果相比,患病人群更為年輕。

Rt pcr showed egfr and egf gene activity were upregulated at the time of blastocyst invasion and adhension , though this upregulation was not directly reflected in an increase in bioactivity egf receptor . at meanwhile , the research of cultured endometrium cell had 本研究有助于進一步探求與子宮內膜接受性密切相關的因子在植入過程中基因表達與調控的信號轉導作用,為進一步研究植入的分子機制提供理論和實踐基礎。

Trophoblastic artery flow were investigated surrounding the intrauterine embryo or within the endometrium . results an endometrial three - line pattern resembled late proliferative endometrium of the normal menstrual cycle were seen in 42 ectopic pregnancy ( 80 . 8 % ) 方法經陰道超聲觀察52例宮外孕及49例宮內孕的子宮內膜變化,并檢測胎囊周邊或子宮內膜內有無滋養動脈血流。

None of ectopic pregnancy had trophoblastic artery flow within the endometrium . conclusion observation of endometrial three - line pattern and trophoblastic artery flow by transvaginal ultrasonography were useful for diagnosing eraly ectopic pregnancy 結論經陰道超聲觀察子宮內膜“三線樣”改變與探測滋養動脈血流對診斷早期宮外孕有重要意義。

Embryo implantation , which is the process of blastocyst adhere and invade endometrium , consists three parts of attachment hydrolysis of extracellular matrix ( ecm ) and invasion 胚胎植入( embryoimplantation )是指胚泡附著并侵入子宮內膜的過程,由粘附、局部細胞外基質水解和侵入三部分構成。

The morphology and structure of most ectopic endometrium were as same as the eutopic endometrium , though there were less epithelium and stroma in ectopic tissues 光鏡觀察見大部分異位子宮內膜形態和結構與在位子宮內膜基本相同,但內膜細胞、間質細胞、腺體,與在位內膜相比較少。

1 harada t , kaponis a , iwabe t , et al . apoptosis in human endometrium and endometriosis . hum reprod update , 2004 , 10 ( 1 ) : 2938 3譚先杰,劉東遠,郎景和,等.子宮內膜腺上皮及基質細胞分離、培養作為子宮內膜異位癥體外細胞模型的探索.現代婦產科進展, 2002 , 11 ( 1 ) : 3032

Liu ' s work involves removing cells from the endometrium , the lining of the womb , then growing layers of these cells on scaffolds of biodegradable material 劉博士研究人造子宮的過程是:從子宮內膜上剝離細胞,然后在能起生物降解作用的物質支架上培育這些細胞。

Successful implantation results from the fine regulated co - operation between the invasive blastocyst and the receptive endometrium 成功的植入取決于胚泡的侵入性和子宮內膜接受性的高度協調。

Expression of mitogen - activated protein kinase and its regulation by ley oligosaccharide in mouse endometrium during implantation 應用小鼠月經模型對子宮內膜血管周期性變化的形態學研究

The er pr her - 2 and be able to bear or endure of medicine and examine in the endometrium kind adenocarcinoma give voice to and significance 2和耐藥檢測在子宮內膜樣腺癌中的表達及意義

Effects of levonorgestrel - releasing intrauterine system on proliferation and apoptosis in eutopic endometrium with endometriosis 曼月樂對子宮內膜異位癥患者在位內膜增殖與凋亡的影響

Temporal and spatial expression of estrogen receptor in the endometrium of patients with endometriosis , adenomyosis or both 子宮內膜異位癥和腺肌癥患者子宮內膜雌激素受體的時空表達

Expression of osteopontin , integrin v subunit and 3 subunit in ectopic and eutopic endometrium in patients with endometriosis 骨橋蛋白和整合素在子宮內膜異位癥中的表達

Expression of transforming growth factor - 1 in the unexplained infertile endometrium at the implantation window 1在不明原因不育癥著床窗期子宮內膜的表達