x

coenzyme

uploads/coenzyme.jpg

coenzyme n.【生物化學】輔酶。

n. 【生物化學】輔酶。 “coenzyme a“ 中文翻譯：   乙酰輔酶a“the coenzyme“ 中文翻譯：   是并列的“coenzyme a radical or reduced coenzyme a“ 中文翻譯：   輔酶a基或還原輔酶a“acetoacetyl coenzyme a“ 中文翻譯：   乙酰乙酰輔酶a“acetyl coenzyme“ 中文翻譯：   乙酰輔酶“acetyl coenzyme a“ 中文翻譯：   乙酰輔酶a“acetyl-coenzyme a“ 中文翻譯：   乙酰輔酶a“acrylyl coenzyme“ 中文翻譯：   丙烯酰輔酶“acyl coenzyme a“ 中文翻譯：   脂肪酰輔酶a; 脂酰輔酶“bacterial coenzyme“ 中文翻譯：   細菌輔酶“butyryl coenzyme“ 中文翻譯：   丁酰輔酶“butyryl coenzyme a“ 中文翻譯：   丁酰輔酶a“butyryl-coenzyme a“ 中文翻譯：   丁酰-輔酶a“carboxylation coenzyme“ 中文翻譯：   羧化輔酶“coa coenzyme“ 中文翻譯：   輔酶“cobamamide coenzyme“ 中文翻譯：   鈷胺酰胺輔酶“cobamide coenzyme“ 中文翻譯：   鈷胺輔酶; 鈷胺素輔酶; 鈷胺酰胺輔酶“coenzyme (a coa)“ 中文翻譯：   輔酶“coenzyme b12“ 中文翻譯：   輔酶 b12“coenzyme complex“ 中文翻譯：   復合輔酶“coenzyme i“ 中文翻譯：   二磷酸吡啶核苷酸“coenzyme ii“ 中文翻譯：   輔酶; 三磷酸吡啶核苷酸; 煙酰胺腺嘌呤二核苷酸磷酸“coenzyme m“ 中文翻譯：   輔酶m“coenzyme nucleosidase“ 中文翻譯：   核苷酶輔酶; 核苷酸輔酶“coenvelope“ 中文翻譯：   上包絡“coenurus skrjabini“ 中文翻譯：   斯氏多頭蚴

Kinetic study shows that nadp + is the only valid coenzyme and that one substrate have no effect on the the other substrates “ bind with the enzyme . products are competitive inhibitors , nadp + / nadph and 6 - phosphogluconate / ribulose - 5 - phosphate pairs are competitive whatever the concentration of the other substrates but noncompetitive versus the other substrates . therefore the kinetic mechanism of the 6 - phosphogluconate dehydrogenase is haldance - laidler - socquet random mechanism 兩種底物與酶的結合互不影響，而在產物抑制效果上， 5一磷酸核酮糖只競爭性抑制6一磷酸葡萄糖酸， nadph只競爭性抑制nadp + ，所以該酶催化機理是haidance一laidier一socquet隨機機理。

coequal

Kinetic study shows that nadp + is the only valid coenzyme and that one substrate have no effect on the the other substrates “ bind with the enzyme . products are competitive inhibitors , nadp + / nadph and 6 - phosphogluconate / ribulose - 5 - phosphate pairs are competitive whatever the concentration of the other substrates but noncompetitive versus the other substrates . therefore the kinetic mechanism of the 6 - phosphogluconate dehydrogenase is haldance - laidler - socquet random mechanism 兩種底物與酶的結合互不影響，而在產物抑制效果上， 5一磷酸核酮糖只競爭性抑制6一磷酸葡萄糖酸， nadph只競爭性抑制nadp + ，所以該酶催化機理是haidance一laidier一socquet隨機機理。

Pharmaessentia estimates that it can develop one new drug per year . for example , the product developed in 2005 is called coenzyme q10 , for which frontier scientific inc . of usa has exclusive distributorship rights internationally . to that end the two companies signed an agreement in august 2005 藥華醫藥目前除了中長期新藥研發，也有短中期產品開發，預計每年開發一項新產品， 2005年的產品為coenzyme q10 ，由美國frontier scientific inc .獨家代理其國際經銷權，雙方已于2005年8月簽訂合約。

It is a medical fact that all living beings need vitamin b12 as a coenzyme in the normal metabolism and reproduction process dna and rna formation of their body cells . a prolonged deficiency of this vitamin can cause a number of illnesses 根據目前醫學所知，任何生物體細胞中的新陳代謝過程及生合成新的細胞時dna及rna的制造步驟，均需要維他命b12當作輔媒coenzyme來完成正常的細胞生長及發育，所以長期缺乏維他命b12常常會引起很多病變。

Recently , there has been rapid development in the research and application of biosensor , which can detect analytes selectively using the specific reaction of bioactive materials such as the enzyme - substrate , enzyme - coenzyme , antigen - antibody , incretion - acceptor and so on 近年來,生物傳感器的研究和應用發展迅猛,它利用生物活性物質的親和性,如酶-底物、酶-輔基、抗原-抗體、激素-受體等的分子識別功能,可以有選擇地檢測待測物。

Lovastatin , the 3 - hydroxy - 3 - methylglutaryl - coenzyme a ( hmg - coa ) reductase inhibitor , is generally applied in the treatment of hypercholesterolemia . it is recently demonstrated that lovastatin inhibits proliferation of tumor cells and triges apoptosis 近年來已有研究發現， lovastatin能夠有效抑制多種腫瘤細胞株增殖并誘導細胞凋亡，關于lovastatin在腫瘤抑制機理及其腫瘤治療效應研究已經受到極大關注。

The electrons are transferred along the chain to a carrier molecule ( coenzyme q ) , and then in sequence to a series of cytochromes , finally acting with the enzyme cytochrome oxidase to reduce an oxygen atom , which combines with two h + ions to form water 電子沿呼吸鏈傳遞到載體分子? ?輔酶q上，然后依次經過一系列細胞色素分子的傳遞，最后與細胞色素氧化酶反應，氧原子結合兩個氫形成水從而被還原。

The mitochondria presents several defense systems , of which the ubiquinone ( coenzyme q10 ) , which is one of the components of the respiratory chain and which has a significant antioxidant function acting upon membrane proteins 線粒體具有幾種防御系統，泛醌（輔酶q10 ）是呼吸鏈的組成成分之一，在膜蛋白質上具有重要的抗氧化功能。

The products range from vitamin a , vitamin d3 , vitamin ad3 , vitamin b12 , coenzyme q10 and cholesterol etc . , which have been exported and supplied to more than 10 countries and regions throughout the world 主要生產維生素a粉(油) 、維生素d3粉(油) 、維生素ad3粉、維生素b12 、輔酶q10 、膽固醇等，產品遠銷全球數十個國家和地區。

The amino group becomes attached to the coenzyme to form pyridoxamine phosphate , and is then transferred to the a - keto acid , which is usually pyruvic acid , oxaloacetic acid , or - ketoglutaric acid 反應中氨基首先連接在輔酶上形成磷酸吡哆氨，然后氨基轉移到-酮酸上，這種-酮酸可以為丙酮酸、草酰乙酸或是-酮戊二酸。

Has made a regain of coenzyme i inside the b cells , thereby create a necessary material conditions for activating the b cells activation by impelling b cells to again fatten , proliferate and regenerate 從而使b細胞得到了重新肥大增殖再生為啟動其生理活性創造了必要的物質條件。這就是內因是決定因素的道理。

Though not definitively proven to work , she often prescribes coenzyme q10 , vitamins e and b6 , quercetin and garlic because laboratory studies have suggested they may be beneficial 她也經常開出服用輔酶q10 ，維生素e和b6 、槲皮苷和大蒜的處方，盡管不能確定它們是否有效，但實驗室研究已表明它們對患者是有益的。

Folic acid is important in metabolism in various coenzyme forms , all of which are specifically concerned with the transfer and utilization of the single carbon ( c1 ) group 與單碳（ c1 ）轉移和利用有關的新陳代謝、各種輔酶形成中起很重要的作用。

Some dehydrogenases are highly specific , with respect to both their substrate and coenzyme , whilst others catalyze the oxidation of a wide range of substrates 一些脫氫酶對于底物和輔酶具有高度的專一性，另一些脫氫酶則能催化各種底物的氧化。

Fad ( flavin adenine dinucleotide ) a derivative of riboflavin that is a coenzyme in electron - transfer reactions 黃素腺嘌呤二核苷酸（ fad ） ：核黃素的衍生物，在電子傳遞反應中是一種輔酶，它作為各種脫氫酶的輔助基團起作用。

Fmn ( flavin mononucleotide ) a derivative of riboflavin that is a coenzyme in electron - transfer reactions 黃素單核苷酸（ fmn ） ：核黃素的衍生物，在電子傳遞反應中是一種輔酶，作為多種脫氫酶的輔助因子起作用。

Dinucleotide a compound of two nucleotides linked by their phosphate groups . important examples are the coenzymes nad and fad 二核苷酸：由磷酸基團連接的兩個核苷酸組成的化合物。例如輔酶nad和fad 。

Coenzyme q ( ubiquinone ) a coenzyme that is an essential component of the respiratory electron - transport chain 輔酶q ：一種在呼吸作用的電子傳遞鏈中起重要作用的輔酶。

This is catalyzed by a transaminase enzyme in conjunction with the coenzyme pyridoxal phosphate 催化這個反應的酶是氨基轉移酶，其上連接有磷酸吡哆醛作為輔酶。