C - citrinin 中文 - EN166

citrinin n.【化學】橘霉素。

citro-
A single direction thin layer chromatography ( stlc ) was researched in order to detect citrinin from above samples , . the results revealed that ethyll acetate : toluene : formic acid ( 6 : 3 : 1 ) was a good developer , then the citrinin from the 29 hongqu samples above were detected , and 6 samples with citrinin less than 0 . 20 g / g ( stlc ) and their strains were screened 第二，以上述29個紅曲樣品為實驗材料，對紅曲中桔霉素的(單向)薄層層析( stlc )條件進行了研究。結果顯示，以甲苯：乙酸乙酯：甲酸( 6 ： 3 ： 1 )為展開劑，桔霉素的分離效果較好。
In this paper , the physical and chemical properties , the toxicological characteristics , the biosynthetic pathway and the detection method of citrinin produced in monascus were introduced and the relative counter measures to eliminate citrinin were also illustrated 介紹了紅曲中產生的桔霉素的理化性質、毒性、產生途徑和檢測方法等的研究現狀，并就如何消除紅曲中桔霉素提出了對策。
And the sample with the highest monacolin k content and its relative strains were acquired . the strain was numbered m12 . finally , monacolin k and citrinin in the sample above were precisely detected again by elisa and hplc respectively 以該方法對6個樣品中的monacolink進行了分析測定，得到1個monacolink含量最高為225 g g ( dtlc )的紅曲樣品及其相應菌株。
Through a series of mutagen tests , a mutant strain of monascus spp ( m 12 - 69 ) from ml2 was acquired , which can produce much higher monacolin k than m12 , and almost same citrinin level as m12 以之為出發菌株，通過誘變篩選，獲得一株monacolink產率有明顯提高而桔霉素產率僅為0 . 13ng g ( elisa )的突變株，編號為m12 - 69 。
The results showed that the content of citrinin and monacolin k from the hongqu samples produced by m12 were 0 . 11 ng / g , 213 , g / g respectively 同時，采用hplc對monacolink進行了分析測定， monacolink含量為213 g g 。將該樣品對應的菌株編號為m12 。
However , citrinin , produced in the growth process of monascus , is a mycotoxin and will induce teratogenicity , carcinogenicity and mutagencity 桔霉素是一種真菌毒素，作用的靶器官是腎臟，可以致畸、誘發腫瘤、突變等。
Accordingly , the discovery of citrinin in monascus brought tremendous dispute about the safety of red starter products 紅曲霉中桔霉素的發現使得我國的紅曲產品的安全性引起爭議。