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antigenicity

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antigenicity n.抗原性。

n. 抗原性。 “antigenicity in vitro“ 中文翻譯：   體外抗原性“antigenicity in vivo“ 中文翻譯：   體內抗原性“antigenicity studies“ 中文翻譯：   抗原性試驗“antigenicity substance“ 中文翻譯：   抗原性物質“cross antigenicity“ 中文翻譯：   交叉抗原性“drug antigenicity“ 中文翻譯：   藥物抗原性“fetal antigenicity“ 中文翻譯：   胎兒抗原性“concept of tumor antigenicity“ 中文翻譯：   腫瘤抗原性概念“antigenicdrift“ 中文翻譯：   抗原漂移,抗原轉變“antigenically negative mutant“ 中文翻譯：   抗原陰性突變株“antigenic variation“ 中文翻譯：   抗原性變異,抗原變異“antigenic variant“ 中文翻譯：   抗原變體“antigenized antibody“ 中文翻譯：   抗原化抗體“antigenic valency“ 中文翻譯：   抗原價

The hbaf53 fragment obtained was used as antigens to immunize a rabbit . in the first immunization , equal volume of freund “ s complete adjuvant was mixed with antigen solution to enhance the antigenicity 用獲得的抗原免疫實驗動物，首次免疫添加等體積的弗氏完全佐劑，以增強抗原的免疫原性。

antigropelos

Finally , comparison of the comprehensive predictions with some of the available experimental information was made . compared with p1 , p2 may be of higher antigenicity . the antigenic sites in p2 were dipersed rather uniformly , including or nearing receptor - activating sites : they are flvldrpeeri , rlrnpsdkfiyat , yrhmekhnyes , rdnklhafiw , asqkcdlvtt , kdspwkqnvs , elkshengf P2片段可能的抗原位點有7個，從氨基端開始依次是flvldrpeeri 、 rlrnpsdkfiyat 、 yrhmekhnyes 、 rdnklhafiw 、 asqkcdlvtt 、 kdspwkqnvs 、 ilkshengf ，分布較均勻，包含有受體激活相關重要位點或與其距離較近。

After that a good renature result was obteined using gradient with lower protein concentration . the purity of the recombinant protein by affinity - purification of glutathione sepharose 4b and electrodialysis method was also attained perfect result . the antigenicity of the gst - ha1 protein were identified using elisa mathod 用梯度透析法對變性的融合蛋白gst - ha1進行復性，在低蛋白濃度的條件下，獲得了很好的復性結果，復性前蛋白濃度為1 . 02mg ml ，復性后蛋白濃度為0 . 875mg ml 。

It is the most important antigen in developing immunity against the virus . in addition , antigenicity and immunogenicity may very depend on the region of ha expressed , and ha1 is the most suitable expression region . in this study , the ha1 gene of a / chicken / guangdong / 2 / 97 ( h5nl ) aiv were cloned by reverse transcription polymerase chain reaction ( rt - pcr ) using primers designed and the sequences and amino acids were analyzed with molecular softpakage 血凝素蛋白( ha )是禽流感病毒最重要的結構蛋白，占囊膜蛋白的90 ，是誘導體液免疫的主要靶抗原，并且還能誘導細胞毒性t細胞作用，另外ha各部分的抗原性和免疫原性也有差別，研究表明， ha1的免疫原性以及抗原性強于ha2 。

Make all these together , it proved that the cloned gene represented the major outer membrane protein gene of ahl316 , and the expressed gene products shared identical antigenicity with the natural main outer membrane protein . the studies on preparation and application of momp - iscoms of ah l316 provided a new approach to fish vaccinology . the successfully cloning and expressing the major outer membrane protein gene of ah l316 made it possible to describe this gene ' s function under a single factor level , and also provided technical support for developing an advanced gene engineering vaccine and subunit vaccine against aeromonas hydrophila 鰻源嗜水氣單胞菌l316主要外膜蛋白免疫刺激復合物的制備與應用研究，對研制魚類疫苗學問題進行了新的初步探索；成功地克隆和表達嗜水氣單胞菌l316主要外膜蛋白基因為在單因子水平上研究嗜水氣單胞菌外膜蛋白的作用和免疫功能以及制備嗜水氣單胞菌基因工程疫苗和亞單位疫苗奠定技術基礎。

Main methods and results are as followed : 1 epitope analysis of agonist - binding region of nrla physicochemical properties and antigenicity of two agonist - binding regions of nrla were analyzed through bioinformatics : domain p1 containing 151 amino acid residues preceding the first transmembrane domain of the human nrla , domain p2 with 144 residues following the third transmembrane domain . four parameters including hopp - woods and kyte hydrophilicityjanin accessibility , karplus - schulz flexibility , and welling antigenicity were used to determine the antigenic sites , and prosite programme and chou - fasman method were employed to analyze their related sequence motif and the secondary structures 用goldkey軟件分別選取公認的hopp等與kyte等親水性參數、 jain表面可及性參數、 karplus - schulz主鏈柔韌性參數及welling抗原性參數對p1 、 p2兩個多肽片段進行參數分析。并采用通用的prosite程序與chou - fasman方法比較分析p1 、 p2多肽片段的氨基酸位點與二級結構特征。綜合判定兩個多肽片段的抗原性及其位點，結果認為p2抗原性強于p1 。

In order to express the recombinant peptide of both gp52 and pp150 oterminal peptides from human cytomegalovirus ( hcmv ) , which seem to show good antigenicity . recombinant dna technology was used to construct recombinant plasmid , which was transformed into the pichia pastoris to express the interesting peptide 為了表達人巨細胞病毒( humancytomegalovirus ， hcmv )中抗原性較強的兩段蛋白片段? gp52c末端和pp150c末端的嵌合肽，用基因工程技術構建適于酵母表達系統的重組表達質粒。

The expressed product was lysised with supersonic wave and purified by sds - page . elisa analysis revealed that the antigenicity of the vpi protein has been detected . the forth part - detection of aev - nh937 strain by in situ hybridization ( 1sh ) - probe was labelled with digoxigenin ( dig ) . then the probe hybrid with 5d , 10d , and 20d postinfection brain tissue of chicken . the results of the ish showed that the positive signal was found in 3 cases , while control group was negative . there has been a reasonable correlatien between this method and other detection test 經超聲波裂解，用尿素溶解包涵體，電泳純化后，利用elisa檢測vp _ 1外殼蛋白，表明具有一定抗原性；第四部分：應用原位雜交檢測aevi用dig標記的探針與sd 、 10d 、 20d的攻毒雞腦組織雜交，來檢測那v的rna 。

The results of our study revealed that h9n2 subtype aiv in the north of henan province during 1998 - 2002 had changed both in antigenicity and ha gene , which provided scientific reference data for prevention against h9n2 aiv and the selection of vaccine strains 本研究結果表明： 1998年一2002年我省豫北地區雞群中比幾亞型禽流感病毒己發生了抗原性漂變，該研究結果從理論上為我國政府制定禽流感撲滅政策、有效地防制hj 。

Expression amount of rhbsag in the former was increased 60 % and 80 % respectively than the latter . antigenicity of pres2 of fusion protein was increased 8 times and 10 times in bmn cells and in pupa hemolymph respectively than nonfusion hbsag Bmpak - hbmp表達的融合m蛋白( pres2 + s )中， pres2抗原性顯著提高，與bmpak - hbm表達的非融合蛋白相比，融合蛋白pres2抗原性在細胞中約提高了8倍，蛹中約提高了1o倍。

In this study , we mainly investigate the antigenicity , immunogenicity of nrla ( nr key subtype ) and the protection of antibody against nr1 in excitotoxicity , which provide experimental foundation for immnotherapeutic strategy against excitotoxicity 本課題主要針對nr主亞基nr1的抗原性、免疫原性及其抗體對興奮毒性神經元損傷保護作用進行充分的研究論證，為興奮毒性腦損傷免疫干預提供實驗基礎。

5 $ methanol . sds - - page showed that after being induced with 0 . 5 % methano1 for 3d , the expressed products existed in supernatant and it ' s molecular weigh was about 22kd , western b1ot showed good antigenicity and speci ficity of expressed product 達產物經sds page檢測表明，轉化于表達了s ：丫hbsagm合蛋白，蛋白分子tie為22kd ， westernblot分析表明，表達蛋白具有較好的抗原性和特異性。

The quantity and quality of hematoblast in umbilical cord blood ( ucb ) can be compared with bone marrow . furthermore , it has other advantages : widely sourced , no contamination of pathogeny , weakly antigenicity , and no mature lymphocyte , et al 臍血中造血細胞的數量和質量都與骨髓相近，而且，具有來源豐富、無病原體污染、抗原性弱、淋巴細胞不成熟等優點。

The results showed the technique suit either completely to immunohistochemical study of the pulp matrix and of the cell surface expression that was weaker antigenicity , or to enzyme histochemical staining of the dental pulp 結果表明，它完全滿足牙髓基質和抗原性較弱的細胞表面標志等成分的免疫組化染色，同時也適用于牙髓的酶組織化學染色。

Ac9 , dg5 and ec9 could still react with csfv shimen strain treated by sds , while cf8 react negatively , indicating the structure is essential to the epitope antigenicity of cf8 單抗ac9 . dg5和ec9與sds處理前后的csfv反應無明顯差異，而cf8不與sds處理后的csfv反應， cf8針對的抗原表位的抗原性與空間構象密切相關。

The hbaf53 fragment obtained was used as antigens to immunize a rabbit . in the first immunization , equal volume of freund “ s complete adjuvant was mixed with antigen solution to enhance the antigenicity 用獲得的抗原免疫實驗動物，首次免疫添加等體積的弗氏完全佐劑，以增強抗原的免疫原性。

The fundamental reasons are : ( 1 ) the sperm / testis specific proteins are autoantigens with low antigenicity , ( 2 ) there are lots of molecules involved the process of fertilization 其根本原因在于( 1 )精子睪丸抗原為自身蛋白，抗原性低下； ( 2 )參與受精過程的分子眾多，作用尚未完全清楚。

Vp2 is one of viral structural proteins on the surface of provirus . its neutralizing antigenicity has been proved . in this study Vp2是鵝細小病毒結構蛋白之一，是gpv的重要保護性抗原，在體內誘導的抗體具有中和作用。

So , the key steps for developing a contraceptive vaccine are selecting the more important molecule ( s ) as target antigen ( s ) and enhancing its antigenicity 因此，解決這一難題的關鍵在于選擇關鍵分子，增強抗原性。